Pseudoresistance to permethrin in scabies

Reports of permethrin resistance of Sarcoptes scabiei var. hominis are emerging. We propose that this may be pseudoresistance. The resistance is due to inadequate counselling by physicians, incorrect treatment (insufficient quantity of permethrin; too short length of treatment), and poor adherence...

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Main Authors: Stefano Veraldi, Rossana Schianchi, Martina Silvio, Italo Francesco Aromolo
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2023-05-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/17750
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author Stefano Veraldi
Rossana Schianchi
Martina Silvio
Italo Francesco Aromolo
author_facet Stefano Veraldi
Rossana Schianchi
Martina Silvio
Italo Francesco Aromolo
author_sort Stefano Veraldi
collection DOAJ
description Reports of permethrin resistance of Sarcoptes scabiei var. hominis are emerging. We propose that this may be pseudoresistance. The resistance is due to inadequate counselling by physicians, incorrect treatment (insufficient quantity of permethrin; too short length of treatment), and poor adherence and compliance by patients. Other reasons include single application of permethrin, suggestion to apply the drug for 6-8 hours, failed application on subungual folds, irritant contact dermatitis, in particular on genitals, for which some patients stop the treatment, and unexplainable use of permethrin in post-scabies prurigo. Thus, we believe that several cases of resistance to permethrin are actually cases of pseudoresistance.
format Article
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institution DOAJ
issn 1972-2680
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publishDate 2023-05-01
publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-776bf193fd954b889e1f15d07b08f88e2025-08-20T02:57:44ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-05-01170510.3855/jidc.17750Pseudoresistance to permethrin in scabiesStefano Veraldi0Rossana Schianchi1Martina Silvio2Italo Francesco Aromolo3Department of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Milan, ItalyEuropean Institute of Dermatology, Milan, ItalyDepartment of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Milan, ItalyDepartment of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy Reports of permethrin resistance of Sarcoptes scabiei var. hominis are emerging. We propose that this may be pseudoresistance. The resistance is due to inadequate counselling by physicians, incorrect treatment (insufficient quantity of permethrin; too short length of treatment), and poor adherence and compliance by patients. Other reasons include single application of permethrin, suggestion to apply the drug for 6-8 hours, failed application on subungual folds, irritant contact dermatitis, in particular on genitals, for which some patients stop the treatment, and unexplainable use of permethrin in post-scabies prurigo. Thus, we believe that several cases of resistance to permethrin are actually cases of pseudoresistance. https://jidc.org/index.php/journal/article/view/17750Sarcoptes scabiei var. hominisscabiespermethrinpseudoresistanceresistance
spellingShingle Stefano Veraldi
Rossana Schianchi
Martina Silvio
Italo Francesco Aromolo
Pseudoresistance to permethrin in scabies
Journal of Infection in Developing Countries
Sarcoptes scabiei var. hominis
scabies
permethrin
pseudoresistance
resistance
title Pseudoresistance to permethrin in scabies
title_full Pseudoresistance to permethrin in scabies
title_fullStr Pseudoresistance to permethrin in scabies
title_full_unstemmed Pseudoresistance to permethrin in scabies
title_short Pseudoresistance to permethrin in scabies
title_sort pseudoresistance to permethrin in scabies
topic Sarcoptes scabiei var. hominis
scabies
permethrin
pseudoresistance
resistance
url https://jidc.org/index.php/journal/article/view/17750
work_keys_str_mv AT stefanoveraldi pseudoresistancetopermethrininscabies
AT rossanaschianchi pseudoresistancetopermethrininscabies
AT martinasilvio pseudoresistancetopermethrininscabies
AT italofrancescoaromolo pseudoresistancetopermethrininscabies