Identification and characterization of cell niches in tissue from spatial omics data at single-cell resolution
Abstract Deciphering the features, structure, and functions of the cell niche in tissues remains a major challenge. Here, we present scNiche, a computational framework to identify and characterize cell niches from spatial omics data at single-cell resolution. We benchmark scNiche with both simulated...
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| Main Authors: | Jingyang Qian, Xin Shao, Hudong Bao, Yin Fang, Wenbo Guo, Chengyu Li, Anyao Li, Hua Hua, Xiaohui Fan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-57029-9 |
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