Parainflammation in the Ocular System: Considerations on the Underlying Mechanisms and Treatment of Dry Eye Disease

Parainflammation in the Ocular System: Considerations on the Underlying Mechanisms and Treatment of Dry Eye Disease

Abstract Introduction The transition from regulated to dysregulated parainflammation is a new concept that needs to be elucidated to clarify the pathogenesis of dry eye disease (DED). This review summarizes the recent evidence about mechanisms that could lead to dysregulated parainflammation, propos...

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Main Authors: Stefano Barabino, Pasquale Aragona, Christophe Baudouin, Kostas Boboridis, José Salgado-Borges, Jose M. Benitez-del-Castillo, Elisabeth M. Messmer, Adriana Stanila, Jutta Horwath-Winter, Edward Wylegala, Maurizio Rolando
Format: Article
Language:English
Published: Adis, Springer Healthcare 2025-03-01
Series:Ophthalmology and Therapy
Subjects:
Parainflammation
Ocular system
Dysfunctional parainflammation
Dry eye disease
Cortisol
Mucins
Online Access:https://doi.org/10.1007/s40123-025-01115-0
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