Lactate and lactylation in liver diseases: energy metabolism, inflammatory immunity and tumor microenvironment
Liver diseases pose a significant threat to human health. Lactate, a byproduct of glycolysis, serves various biological functions, including acting as an energy source, a signaling molecule, and a substrate for lactylation. Lactylation is a novel lactate-dependent post-translational modification tha...
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| Main Authors: | Shiyi Cheng, Xiaoyu Xiao, Dingye Wang, Xiyuan Wang, Minlan Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581582/full |
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