Radiation from frequent whole-body CT scans induces systemic immunosuppression and immune activation of tumor tissue

Radiation from frequent whole-body CT scans induces systemic immunosuppression and immune activation of tumor tissue

Abstracts: Objective: This study aims to elucidate the impact of repeated whole-body computed tomography (CT) scans on systemic immunity, the tumor immune microenvironment, and tumor control. This inquiry was prompted by clinical observations indicating a decrease in the levels of IFN-β and IFN-γ i...

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Bibliographic Details
Main Authors: Jigang Dong, Chengrui Fu, Minghao Li, Zhongtang Wang, Baosheng Li
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Translational Oncology
Subjects:
Whole-body CT scanning radiation
Low-dose radiation
IFN
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325000579
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