T1 Thermometry for Deep Brain Stimulation Applications: A Comparison between Rapid Gradient Echo Sequences

Background: T1 thermometry is considered a straight method for the safety monitoring of patients with deep brain stimulation (DBS) electrodes against radiofrequency-induced heating during Magnetic Resonance Imaging (MRI), requiring different sequences and methods.Objective: This study aimed to compa...

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Bibliographic Details
Main Authors: Zinat Zarrini-Monfared, Mansour Parvaresh, Mehdi Mohammad Mirbagheri
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2024-12-01
Series:Journal of Biomedical Physics and Engineering
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Online Access:https://jbpe.sums.ac.ir/article_49271_7a1d94cab7d32cfd3f970a1f3e4d4818.pdf
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Summary:Background: T1 thermometry is considered a straight method for the safety monitoring of patients with deep brain stimulation (DBS) electrodes against radiofrequency-induced heating during Magnetic Resonance Imaging (MRI), requiring different sequences and methods.Objective: This study aimed to compare two T1 thermometry methods and two low specific absorption rate (SAR) imaging sequences in terms of the output image quality.Material and Methods: In this experimental study, a gel phantom was prepared, resembling the brain tissue properties with a copper wire inside. Two types of rapid gradient echo sequences, namely radiofrequency-spoiled and balanced steady-state free precession (bSSFP) sequences, were used. T1 thermometry was performed by either T1-weighted images with a high SAR sequence to increase heating around the wire or T1 mapping methods.Results: The balanced steady-state free precession (bSSFP) sequence provided higher image quality in terms of spatial resolution (1×1×1.5 mm3 compared with 1×1×3 mm3) at a shorter acquisition time. The susceptibility artifact was also less pronounced for the bSSFP sequence compared with the radiofrequency-spoiled sequence. A temperature increase, of up to 8 ℃, was estimated using a high SAR sequence. The estimated change in temperature was reduced when using the T1 mapping method. Conclusion: Heating induced during MRI of implanted electrodes could be estimated using high-resolution T1 maps obtained from inversion recovery bSSFP sequence. Such a method gives a direct estimation of heating during the imaging sequence, which is highly desirable for safe MRI of DBS patients.
ISSN:2251-7200