Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy
As one of the most common microvascular complications of diabetes mellitus, diabetic nephropathy（DN）is a common cause of end-stage renal disease（ESRD）.Sodium-glucose cotransporter 2（SGLT-2）inhibitor, a new type of hypoglycemic agent, may effectively lower blood glucose, improve renal hyperfiltration...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2021-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57905330&Fpath=home&index=0 |
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| _version_ | 1850143345432592384 |
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| author | Kong Ling-li Sun Yuan-bo Wang Xiao-li Ren Ming-yu Li Gui-qin |
| author_facet | Kong Ling-li Sun Yuan-bo Wang Xiao-li Ren Ming-yu Li Gui-qin |
| author_sort | Kong Ling-li |
| collection | DOAJ |
| description | As one of the most common microvascular complications of diabetes mellitus, diabetic nephropathy（DN）is a common cause of end-stage renal disease（ESRD）.Sodium-glucose cotransporter 2（SGLT-2）inhibitor, a new type of hypoglycemic agent, may effectively lower blood glucose, improve renal hyperfiltration, lower blood pressure, reduce urinary protein, improve renal hypoxia, reduce inflammation and oxidative stress, lower serum uric acid, weight and plasma lipids, etc.This review summarized its protective mechanism on DN. |
| format | Article |
| id | doaj-art-7748edb7debe4e2799fed1e5fc3192c0 |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2021-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-7748edb7debe4e2799fed1e5fc3192c02025-08-20T02:28:45ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-012133834257905330Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathyKong Ling-liSun Yuan-boWang Xiao-liRen Ming-yuLi Gui-qinAs one of the most common microvascular complications of diabetes mellitus, diabetic nephropathy（DN）is a common cause of end-stage renal disease（ESRD）.Sodium-glucose cotransporter 2（SGLT-2）inhibitor, a new type of hypoglycemic agent, may effectively lower blood glucose, improve renal hyperfiltration, lower blood pressure, reduce urinary protein, improve renal hypoxia, reduce inflammation and oxidative stress, lower serum uric acid, weight and plasma lipids, etc.This review summarized its protective mechanism on DN.http://www.lcszb.com/thesisDetails?columnId=57905330&Fpath=home&index=0Sodium-glucose cotransporter 2 inhibitorsSodium-glucose cotransporterDiabetic nephropathy |
| spellingShingle | Kong Ling-li Sun Yuan-bo Wang Xiao-li Ren Ming-yu Li Gui-qin Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy Linchuang shenzangbing zazhi Sodium-glucose cotransporter 2 inhibitors Sodium-glucose cotransporter Diabetic nephropathy |
| title | Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy |
| title_full | Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy |
| title_fullStr | Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy |
| title_full_unstemmed | Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy |
| title_short | Sodium-glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy |
| title_sort | sodium glucose cotransporter 2 inhibitor for the treatment of diabetic nephropathy |
| topic | Sodium-glucose cotransporter 2 inhibitors Sodium-glucose cotransporter Diabetic nephropathy |
| url | http://www.lcszb.com/thesisDetails?columnId=57905330&Fpath=home&index=0 |
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