LPCAT3 regulates the proliferation and metastasis of serous ovarian cancer by modulating arachidonic acid

LPCAT3 regulates the proliferation and metastasis of serous ovarian cancer by modulating arachidonic acid

Background: Lysophosphatidylcholine acyltransferase 3 (LPCAT3) promotes ferroptosis through the incorporating polyunsaturated fatty acids into membrane phospholipids, however, its role in serous ovarian cancer remains unclear. Here explored cancer proliferation and metastasis after modulating LPCAP3...

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Bibliographic Details
Main Authors: Fang Wen, Hongjian Ling, Rui Ran, Xinya Li, Houmei Wang, Qianfen Liu, Min Li, Tinghe Yu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Translational Oncology
Subjects:
Ovarian cancer
LPCAT3
Lipid metabolism
Arachidonic acid
Ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324003826
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