Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western Iraq
The goal of this work is to determine the prevalence of asymptomatic bacteriuria (ASB) during pregnancy, identify the causative organisms, and analyze the antibiotic susceptibility pattern of the isolates. This study was conducted on 139 pregnant women in Iraq. Clinically, all the women had no sympt...
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Galenos Publishing House
2025-07-01
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| Series: | Gazi Medical Journal |
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| Online Access: | https://gazimedj.com/articles/antibiotic-sensitivity-of-microbial-isolates-causing-asymptomatic-bacteriuria-during-pregnancy-in-general-heet-hospital-western-iraq/doi/gmj.2025.4244 |
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| author | Ahmed Saadoun Jaloot Mustafa Nadhim Owaid Nawal Aziz Baker |
| author_facet | Ahmed Saadoun Jaloot Mustafa Nadhim Owaid Nawal Aziz Baker |
| author_sort | Ahmed Saadoun Jaloot |
| collection | DOAJ |
| description | The goal of this work is to determine the prevalence of asymptomatic bacteriuria (ASB) during pregnancy, identify the causative organisms, and analyze the antibiotic susceptibility pattern of the isolates. This study was conducted on 139 pregnant women in Iraq. Clinically, all the women had no symptoms of a urinary tract infection. Clean catch midstream urine samples were collected from all patients. The microscopic and cultural methods were used to check all urine samples. Identification of isolates was performed using the VITEK 2 system and antibiotic sensitivity was assessed using the same technique. The results showed that 70 (50.36%) of the 139 pregnant women tested positive for ASB. The age group of 15-20 years had the highest prevalence (60.86%) of ASB. The most common etiological agent causing infections among pregnant women was Staphylococcus species (66.65%), followed by Escherichia coli (E. coli) (10.52%), and Klebsiella pneumoniae (K. pneumoniae) (8.77%). Also, the susceptibility pattern of E. coli and K. pneumoniae showed that most of the isolates were highly sensitive (100%) to piperacillin/tazobactam, ertapenem, imipenem, amikacin, gentamicin, ciprofloxacin, levofloxacin, and tigecyclin. E. coli isolates were highly sensitive to cefoxitin (100%). Coliforms (E. coli and K. pneumoniae ) were highly resistant to β-lactams, including : ampicillin (100%), ceftazidime (100%), cefazolin (100%), ceftriaxone (100%), and ciprofloxacin (100%). Based on the resistance profiles, all isolates of K. pneumoniae and E. coli (100%) were extended-spectrum beta-actamase producers. |
| format | Article |
| id | doaj-art-7732005a4b8a4512b24e7cc33816c40a |
| institution | Kabale University |
| issn | 2147-2092 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Gazi Medical Journal |
| spelling | doaj-art-7732005a4b8a4512b24e7cc33816c40a2025-08-20T03:51:18ZengGalenos Publishing HouseGazi Medical Journal2147-20922025-07-0136325526510.12996/gmj.2025.4244Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western IraqAhmed Saadoun Jaloot0https://orcid.org/0000-0002-8753-4333Mustafa Nadhim Owaid1https://orcid.org/0000-0001-9005-4368Nawal Aziz Baker2https://orcid.org/0009-0003-7130-233XDepartment of Medical Physics, College of Applied Sciences-Heet, University of Anbar, Hit, IraqDepartment of Medical Physics, College of Applied Sciences-Heet, University of Anbar, Hit, IraqDepartment of Obstetrics and Gynecology, General Heet Hospital, Ministry of Health, Hit, IraqThe goal of this work is to determine the prevalence of asymptomatic bacteriuria (ASB) during pregnancy, identify the causative organisms, and analyze the antibiotic susceptibility pattern of the isolates. This study was conducted on 139 pregnant women in Iraq. Clinically, all the women had no symptoms of a urinary tract infection. Clean catch midstream urine samples were collected from all patients. The microscopic and cultural methods were used to check all urine samples. Identification of isolates was performed using the VITEK 2 system and antibiotic sensitivity was assessed using the same technique. The results showed that 70 (50.36%) of the 139 pregnant women tested positive for ASB. The age group of 15-20 years had the highest prevalence (60.86%) of ASB. The most common etiological agent causing infections among pregnant women was Staphylococcus species (66.65%), followed by Escherichia coli (E. coli) (10.52%), and Klebsiella pneumoniae (K. pneumoniae) (8.77%). Also, the susceptibility pattern of E. coli and K. pneumoniae showed that most of the isolates were highly sensitive (100%) to piperacillin/tazobactam, ertapenem, imipenem, amikacin, gentamicin, ciprofloxacin, levofloxacin, and tigecyclin. E. coli isolates were highly sensitive to cefoxitin (100%). Coliforms (E. coli and K. pneumoniae ) were highly resistant to β-lactams, including : ampicillin (100%), ceftazidime (100%), cefazolin (100%), ceftriaxone (100%), and ciprofloxacin (100%). Based on the resistance profiles, all isolates of K. pneumoniae and E. coli (100%) were extended-spectrum beta-actamase producers.https://gazimedj.com/articles/antibiotic-sensitivity-of-microbial-isolates-causing-asymptomatic-bacteriuria-during-pregnancy-in-general-heet-hospital-western-iraq/doi/gmj.2025.4244antibiotic susceptibility testasymptomatic bacteriuriaantibacterial agenturinary tract infectionpregnancy |
| spellingShingle | Ahmed Saadoun Jaloot Mustafa Nadhim Owaid Nawal Aziz Baker Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western Iraq Gazi Medical Journal antibiotic susceptibility test asymptomatic bacteriuria antibacterial agent urinary tract infection pregnancy |
| title | Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western Iraq |
| title_full | Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western Iraq |
| title_fullStr | Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western Iraq |
| title_full_unstemmed | Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western Iraq |
| title_short | Antibiotic Sensitivity of Microbial Isolates Causing Asymptomatic Bacteriuria During Pregnancy, in General Heet Hospital, Western Iraq |
| title_sort | antibiotic sensitivity of microbial isolates causing asymptomatic bacteriuria during pregnancy in general heet hospital western iraq |
| topic | antibiotic susceptibility test asymptomatic bacteriuria antibacterial agent urinary tract infection pregnancy |
| url | https://gazimedj.com/articles/antibiotic-sensitivity-of-microbial-isolates-causing-asymptomatic-bacteriuria-during-pregnancy-in-general-heet-hospital-western-iraq/doi/gmj.2025.4244 |
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