Contact-free magnetic resonance imaging and spectroscopy with acoustic levitation
Abstract Conventional magnetic resonance measurements often rely on the use of sample containers. This limits the implementation of time-resolved studies at the molecular level of liquid samples undergoing evaporation or other dynamic phenomena that require access to the liquid-gas interface. In thi...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-58949-2 |
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| author | Smaragda-Maria Argyri Leo Svenningsson Feryal Guerroudj Diana Bernin Lars Evenäs Romain Bordes |
| author_facet | Smaragda-Maria Argyri Leo Svenningsson Feryal Guerroudj Diana Bernin Lars Evenäs Romain Bordes |
| author_sort | Smaragda-Maria Argyri |
| collection | DOAJ |
| description | Abstract Conventional magnetic resonance measurements often rely on the use of sample containers. This limits the implementation of time-resolved studies at the molecular level of liquid samples undergoing evaporation or other dynamic phenomena that require access to the liquid-gas interface. In this study, we developed a demagnetized acoustic levitator to perform magnetic resonance studies on liquid samples, in a contact-free manner. The performance of the levitator inside a 7.05 T magnetic field was examined and magnetic resonance images of the levitator and the levitated samples were acquired. Then, we collected magnetic resonance spectra of the levitated droplets by applying localized and non-localized pulse sequences and we examined the effect of the droplet shape on the chemical shift. Additionally, we conducted time-resolved experiments on pure solvents and mixtures, and captured physical and chemical molecular interactions, in real-time. This approach enables contact-free studies at the molecular level of dynamic phenomena on a microliter droplet using magnetic resonance techniques. |
| format | Article |
| id | doaj-art-772269bc6c7d4a9e95cabdb762138d18 |
| institution | OA Journals |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-772269bc6c7d4a9e95cabdb762138d182025-08-20T02:30:18ZengNature PortfolioNature Communications2041-17232025-04-011611910.1038/s41467-025-58949-2Contact-free magnetic resonance imaging and spectroscopy with acoustic levitationSmaragda-Maria Argyri0Leo Svenningsson1Feryal Guerroudj2Diana Bernin3Lars Evenäs4Romain Bordes5Department of Chemistry and Chemical Engineering, Chalmers University of TechnologyDepartment of Chemistry and Chemical Engineering, Chalmers University of TechnologyDepartment of Chemistry and Chemical Engineering, Chalmers University of TechnologyDepartment of Chemistry and Chemical Engineering, Chalmers University of TechnologyDepartment of Chemistry and Chemical Engineering, Chalmers University of TechnologyDepartment of Chemistry and Chemical Engineering, Chalmers University of TechnologyAbstract Conventional magnetic resonance measurements often rely on the use of sample containers. This limits the implementation of time-resolved studies at the molecular level of liquid samples undergoing evaporation or other dynamic phenomena that require access to the liquid-gas interface. In this study, we developed a demagnetized acoustic levitator to perform magnetic resonance studies on liquid samples, in a contact-free manner. The performance of the levitator inside a 7.05 T magnetic field was examined and magnetic resonance images of the levitator and the levitated samples were acquired. Then, we collected magnetic resonance spectra of the levitated droplets by applying localized and non-localized pulse sequences and we examined the effect of the droplet shape on the chemical shift. Additionally, we conducted time-resolved experiments on pure solvents and mixtures, and captured physical and chemical molecular interactions, in real-time. This approach enables contact-free studies at the molecular level of dynamic phenomena on a microliter droplet using magnetic resonance techniques.https://doi.org/10.1038/s41467-025-58949-2 |
| spellingShingle | Smaragda-Maria Argyri Leo Svenningsson Feryal Guerroudj Diana Bernin Lars Evenäs Romain Bordes Contact-free magnetic resonance imaging and spectroscopy with acoustic levitation Nature Communications |
| title | Contact-free magnetic resonance imaging and spectroscopy with acoustic levitation |
| title_full | Contact-free magnetic resonance imaging and spectroscopy with acoustic levitation |
| title_fullStr | Contact-free magnetic resonance imaging and spectroscopy with acoustic levitation |
| title_full_unstemmed | Contact-free magnetic resonance imaging and spectroscopy with acoustic levitation |
| title_short | Contact-free magnetic resonance imaging and spectroscopy with acoustic levitation |
| title_sort | contact free magnetic resonance imaging and spectroscopy with acoustic levitation |
| url | https://doi.org/10.1038/s41467-025-58949-2 |
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