Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis
Clinical and experimental studies have shown that opisthorchii tend to evade tumour growth foci to colonize more distant areas of the liver. When modelling tumours with various carcinogens in the setting of superinvasive opisthorchiasis, the intensity of invasion is reduced both before the formation...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.1155/2019/8079368 |
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| author | Vitaly G. Bychkov Ludmila F. Kalyonova Elena D. Khadieva Semen D. Lazarev Ilgiz R. Lukmanov Vladimir A. Shidin Evgeny N. Morozov |
| author_facet | Vitaly G. Bychkov Ludmila F. Kalyonova Elena D. Khadieva Semen D. Lazarev Ilgiz R. Lukmanov Vladimir A. Shidin Evgeny N. Morozov |
| author_sort | Vitaly G. Bychkov |
| collection | DOAJ |
| description | Clinical and experimental studies have shown that opisthorchii tend to evade tumour growth foci to colonize more distant areas of the liver. When modelling tumours with various carcinogens in the setting of superinvasive opisthorchiasis, the intensity of invasion is reduced both before the formation of neoplasms (>120 days) and after the development of tumours of various histogeneses (liver, pancreas, and stomach) (>240 days). Egg production was observed to increase with the decrease in the number of parasites in the liver. The smallest changes in the infestation intensity indicators and egg production were observed in the experimental stomach tumours (p>0.05). A partial hepatectomy in the setting of opisthorchiasis did not affect the number of parasites in the ecological niche (liver) or the production of eggs by the helminth. With the deterioration of the vegetation state, parasite clumps of opisthorchii increase egg production under the conditions of distress. |
| format | Article |
| id | doaj-art-7716a65888b74e448fa4b747b0bf2fc0 |
| institution | Kabale University |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-7716a65888b74e448fa4b747b0bf2fc02025-08-20T03:35:45ZengWileyAnalytical Cellular Pathology2210-71772210-71852019-01-01201910.1155/2019/80793688079368Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive OpisthorchiasisVitaly G. Bychkov0Ludmila F. Kalyonova1Elena D. Khadieva2Semen D. Lazarev3Ilgiz R. Lukmanov4Vladimir A. Shidin5Evgeny N. Morozov6Tyumen State Medical University, Tyumen, RussiaTyumen Scientific Centre, Tyumen, RussiaKhanty-Mansiysk State Medical Academy, Khanty-Mansiysk, RussiaTyumen State Medical University, Tyumen, RussiaKhanty-Mansiysk State Medical Academy, Khanty-Mansiysk, RussiaTyumen State Medical University, Tyumen, RussiaSechenov University, Moscow, RussiaClinical and experimental studies have shown that opisthorchii tend to evade tumour growth foci to colonize more distant areas of the liver. When modelling tumours with various carcinogens in the setting of superinvasive opisthorchiasis, the intensity of invasion is reduced both before the formation of neoplasms (>120 days) and after the development of tumours of various histogeneses (liver, pancreas, and stomach) (>240 days). Egg production was observed to increase with the decrease in the number of parasites in the liver. The smallest changes in the infestation intensity indicators and egg production were observed in the experimental stomach tumours (p>0.05). A partial hepatectomy in the setting of opisthorchiasis did not affect the number of parasites in the ecological niche (liver) or the production of eggs by the helminth. With the deterioration of the vegetation state, parasite clumps of opisthorchii increase egg production under the conditions of distress.http://dx.doi.org/10.1155/2019/8079368 |
| spellingShingle | Vitaly G. Bychkov Ludmila F. Kalyonova Elena D. Khadieva Semen D. Lazarev Ilgiz R. Lukmanov Vladimir A. Shidin Evgeny N. Morozov Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis Analytical Cellular Pathology |
| title | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
| title_full | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
| title_fullStr | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
| title_full_unstemmed | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
| title_short | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
| title_sort | dynamics of the o felineus infestation intensity and egg production in carcinogenesis and partial hepatectomy in the setting of superinvasive opisthorchiasis |
| url | http://dx.doi.org/10.1155/2019/8079368 |
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