Targeted ultra-high performance liquid chromatography-tandem mass spectrometry assay for the quantification of medium-chain phosphatidylcholines in platelets of coronary artery disease patients

Targeted ultra-high performance liquid chromatography-tandem mass spectrometry assay for the quantification of medium-chain phosphatidylcholines in platelets of coronary artery disease patients

In a recent untargeted clinical lipidomics study of platelets of coronary artery disease (CAD) patients, medium-chain phosphatidylcholines (MCPCs) with C8 and C10 fatty acyl residues were found significantly upregulated in the patient group with acute coronary syndrome (ACS) as compared to chronic c...

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Bibliographic Details
Main Authors: Tamara Janker, Adrian Brun, Adrian Sievers-Engler, Kristina Dittrich, Meinrad Gawaz, Michael Lämmerhofer
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Chromatography Open
Subjects:
Biomarker
Clinical lipidomics
Mass spectrometry
Phospholipids
Acute coronary syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S2772391724000471
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