A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case report

Abstract Background Capnocytophaga spp. is associated with fulminant sepsis, particularly in those with immunosuppression. We here report a rare case of fatal fulminant septic shock caused by C. gingivalis, concurrent with COVID‐19. Case Presentation A Japanese woman developed septic shock, which le...

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Main Authors: Dai Miyazaki, Chika Kunishige, Shigeru Sano, Kahoru Urakawa, Kana Okamoto, Naomi Morishita, Kentaro Iwata
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Acute Medicine & Surgery
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Online Access:https://doi.org/10.1002/ams2.922
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author Dai Miyazaki
Chika Kunishige
Shigeru Sano
Kahoru Urakawa
Kana Okamoto
Naomi Morishita
Kentaro Iwata
author_facet Dai Miyazaki
Chika Kunishige
Shigeru Sano
Kahoru Urakawa
Kana Okamoto
Naomi Morishita
Kentaro Iwata
author_sort Dai Miyazaki
collection DOAJ
description Abstract Background Capnocytophaga spp. is associated with fulminant sepsis, particularly in those with immunosuppression. We here report a rare case of fatal fulminant septic shock caused by C. gingivalis, concurrent with COVID‐19. Case Presentation A Japanese woman developed septic shock, which led to her death. Polymerase chain reaction (PCR) testing of the respiratory specimen was positive for SARS‐CoV‐2, and a CT scan of the chests revealed bilateral ground glass opacities. The blood cultures identified C. gingivalis. The patient had rheumatoid arthritis and was taking prednisone orally. There were no splenic abnormalities shown on the CT scan. Conclusion A rare case of fulminant septic shock caused by C. gingivalis, together with COVID‐19 was identified. The precise pathogenesis of this combination, together with the best treatment option should be sought by further studies.
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spelling doaj-art-7710dc1af74c4c5fb45dc266cc491bed2025-08-20T02:52:53ZengWileyAcute Medicine & Surgery2052-88172024-01-01111n/an/a10.1002/ams2.922A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case reportDai Miyazaki0Chika Kunishige1Shigeru Sano2Kahoru Urakawa3Kana Okamoto4Naomi Morishita5Kentaro Iwata6Department of Emergency Medicine Hyogo Prefectural Kakogawa Medical Center Kakogawa JapanDepartment of Emergency Medicine Hyogo Prefectural Kakogawa Medical Center Kakogawa JapanDepartment of Emergency Medicine Hyogo Prefectural Kakogawa Medical Center Kakogawa JapanDepartment of Clinical Laboratory Hyogo Prefectural Kakogawa Medical Center Kakogawa JapanDepartment of Clinical Laboratory Hyogo Prefectural Kakogawa Medical Center Kakogawa JapanDepartment of Nursing Hyogo Prefectural Kakogawa Medical Center Kakogawa JapanDivision of Infectious Diseases Kobe University Hospital Kobe JapanAbstract Background Capnocytophaga spp. is associated with fulminant sepsis, particularly in those with immunosuppression. We here report a rare case of fatal fulminant septic shock caused by C. gingivalis, concurrent with COVID‐19. Case Presentation A Japanese woman developed septic shock, which led to her death. Polymerase chain reaction (PCR) testing of the respiratory specimen was positive for SARS‐CoV‐2, and a CT scan of the chests revealed bilateral ground glass opacities. The blood cultures identified C. gingivalis. The patient had rheumatoid arthritis and was taking prednisone orally. There were no splenic abnormalities shown on the CT scan. Conclusion A rare case of fulminant septic shock caused by C. gingivalis, together with COVID‐19 was identified. The precise pathogenesis of this combination, together with the best treatment option should be sought by further studies.https://doi.org/10.1002/ams2.922CapnocytophagaCOVID‐19sepsis
spellingShingle Dai Miyazaki
Chika Kunishige
Shigeru Sano
Kahoru Urakawa
Kana Okamoto
Naomi Morishita
Kentaro Iwata
A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case report
Acute Medicine & Surgery
Capnocytophaga
COVID‐19
sepsis
title A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case report
title_full A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case report
title_fullStr A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case report
title_full_unstemmed A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case report
title_short A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID‐19: A case report
title_sort fatal septic shock caused by capnocytophaga gingivalis potentially associated with covid 19 a case report
topic Capnocytophaga
COVID‐19
sepsis
url https://doi.org/10.1002/ams2.922
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