Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders
Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxi...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2007.139 |
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| author | Emanuela Masini Danielle Bani Cosimo Marzocca Mircea Alexandru Mateescu Pier Francesco Mannaioni Rodolfo Federico Bruno Mondovì |
| author_facet | Emanuela Masini Danielle Bani Cosimo Marzocca Mircea Alexandru Mateescu Pier Francesco Mannaioni Rodolfo Federico Bruno Mondovì |
| author_sort | Emanuela Masini |
| collection | DOAJ |
| description | Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported. |
| format | Article |
| id | doaj-art-770fa0ee56a347f6b88f56ff95381107 |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-770fa0ee56a347f6b88f56ff953811072025-08-20T02:07:35ZengWileyThe Scientific World Journal1537-744X2007-01-01788890210.1100/tsw.2007.139Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory DisordersEmanuela Masini0Danielle Bani1Cosimo Marzocca2Mircea Alexandru Mateescu3Pier Francesco Mannaioni4Rodolfo Federico5Bruno Mondovì6Department of Preclinical and Clinical Pharmacology, University of Florence, ItalyDepartment of Anatomy, Histology and Forensic Medicine, Section of Histology, University of Florence, ItalyDepartment of Preclinical and Clinical Pharmacology, University of Florence, ItalyDepartment of Chemistry and Biochemistry, Université du Québec à Montréal, Montreal (Quebec), CanadaDepartment of Preclinical and Clinical Pharmacology, University of Florence, ItalyDepartment of Biology, University of Rome, ItalyDepartment of Biochemical Sciences “A. Rossi Fanelli”, Rome University “La Sapienza”, Rome, ItalyAmine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported.http://dx.doi.org/10.1100/tsw.2007.139 |
| spellingShingle | Emanuela Masini Danielle Bani Cosimo Marzocca Mircea Alexandru Mateescu Pier Francesco Mannaioni Rodolfo Federico Bruno Mondovì Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders The Scientific World Journal |
| title | Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders |
| title_full | Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders |
| title_fullStr | Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders |
| title_full_unstemmed | Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders |
| title_short | Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders |
| title_sort | pea seedling histaminase as a novel therapeutic approach to anaphylactic and inflammatory disorders |
| url | http://dx.doi.org/10.1100/tsw.2007.139 |
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