Diffuse Large B-Cell Lymphoma with Calf Muscle Localization

Although diffuse large B-cell lymphoma (DLBCL) usually occurs in the lymph nodes, approximately 30–40% of the time it can have an extranodal site of involvement and it can arise in nearly every body site such as intestine, bone, breast, liver, skin, lung, and central nervous system. Muscle involveme...

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Main Authors: Laura Bourdeanu, Rashmi Menon, George Somlo
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2011/292494
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author Laura Bourdeanu
Rashmi Menon
George Somlo
author_facet Laura Bourdeanu
Rashmi Menon
George Somlo
author_sort Laura Bourdeanu
collection DOAJ
description Although diffuse large B-cell lymphoma (DLBCL) usually occurs in the lymph nodes, approximately 30–40% of the time it can have an extranodal site of involvement and it can arise in nearly every body site such as intestine, bone, breast, liver, skin, lung, and central nervous system. Muscle involvement of DLBCL is especially uncommon, comprising 0.5% of extranodal NHL. We report a case of a 72-year-old man with extranodal DLBCL of a unique manifestation in the calf muscle, involving predominantly the gastrocnemius muscle. The patient achieved complete response and remained free of local recurrence or metastasis following diagnosis.
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series Case Reports in Hematology
spelling doaj-art-770e4b4a5f044f9598090c00f3058e6a2025-02-03T01:09:42ZengWileyCase Reports in Hematology2090-65602090-65792011-01-01201110.1155/2011/292494292494Diffuse Large B-Cell Lymphoma with Calf Muscle LocalizationLaura Bourdeanu0Rashmi Menon1George Somlo2Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, 1500 E Duarte Road, Duarte, CA 91010, USADepartment of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, 1500 E Duarte Road, Duarte, CA 91010, USADepartment of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, 1500 E Duarte Road, Duarte, CA 91010, USAAlthough diffuse large B-cell lymphoma (DLBCL) usually occurs in the lymph nodes, approximately 30–40% of the time it can have an extranodal site of involvement and it can arise in nearly every body site such as intestine, bone, breast, liver, skin, lung, and central nervous system. Muscle involvement of DLBCL is especially uncommon, comprising 0.5% of extranodal NHL. We report a case of a 72-year-old man with extranodal DLBCL of a unique manifestation in the calf muscle, involving predominantly the gastrocnemius muscle. The patient achieved complete response and remained free of local recurrence or metastasis following diagnosis.http://dx.doi.org/10.1155/2011/292494
spellingShingle Laura Bourdeanu
Rashmi Menon
George Somlo
Diffuse Large B-Cell Lymphoma with Calf Muscle Localization
Case Reports in Hematology
title Diffuse Large B-Cell Lymphoma with Calf Muscle Localization
title_full Diffuse Large B-Cell Lymphoma with Calf Muscle Localization
title_fullStr Diffuse Large B-Cell Lymphoma with Calf Muscle Localization
title_full_unstemmed Diffuse Large B-Cell Lymphoma with Calf Muscle Localization
title_short Diffuse Large B-Cell Lymphoma with Calf Muscle Localization
title_sort diffuse large b cell lymphoma with calf muscle localization
url http://dx.doi.org/10.1155/2011/292494
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AT rashmimenon diffuselargebcelllymphomawithcalfmusclelocalization
AT georgesomlo diffuselargebcelllymphomawithcalfmusclelocalization