Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week)
Aim. Presentation of the Forum “Deprescribing and optimal selection of proton pump inhibitors” held in Moscow on 29 September 2020 during the 26th United Russian Gastroenterology Week.Key points. The Forum was aimed at discussing issues associated with improving the proton pump inhibitor (PPIs) ther...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2020-12-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/535 |
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| author | V. T. Ivashkin I. V. Maev A. S. Trukhmanov A. A. Sheptulin V. I. Simanenkov T. L. Lapina I. B. Khlynov N. N. Dekhnich O. D. Lopina O. P. Alekseeva N. V. Korochanskaya M. F. Osipenko P. V. Pavlov S. S. Pirogov G. N. Tarasova Yu. P. Uspenskiy D. N. Andreev D. E. Rumyantseva |
| author_facet | V. T. Ivashkin I. V. Maev A. S. Trukhmanov A. A. Sheptulin V. I. Simanenkov T. L. Lapina I. B. Khlynov N. N. Dekhnich O. D. Lopina O. P. Alekseeva N. V. Korochanskaya M. F. Osipenko P. V. Pavlov S. S. Pirogov G. N. Tarasova Yu. P. Uspenskiy D. N. Andreev D. E. Rumyantseva |
| author_sort | V. T. Ivashkin |
| collection | DOAJ |
| description | Aim. Presentation of the Forum “Deprescribing and optimal selection of proton pump inhibitors” held in Moscow on 29 September 2020 during the 26th United Russian Gastroenterology Week.Key points. The Forum was aimed at discussing issues associated with improving the proton pump inhibitor (PPIs) therapy in treatment and prevention of acid-related diseases and upper gastrointestinal tract (GIT) disorders induced by non-steroidal anti-inflammatory drugs (NSAIDs) and antiplatelet medications. Deprescribing is considered to be an effective strategy of a motivated reduction of the PPI dosage, duration of therapy and the patient’s transfer from a regular to on-demand intake regimen. The choice of PPI may condition an optimal therapy for acid-related diseases.Conclusion. PPIs prevail in therapies for acid-related diseases and NSAID-induced upper GIT lesions. PPI deprescribing should be a strategy of choice if medically indicated. A non-enzymatic metabolism, high acid suppression, stable antisecretory effect from day 1 of therapy and cytoprotective action justify the application of rabeprazole (Pariet®) for optimising therapies for acid-related diseases and implementing the deprescribing strategy. |
| format | Article |
| id | doaj-art-7709482ab71546e6943c9ea42d10f61a |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2020-12-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-7709482ab71546e6943c9ea42d10f61a2025-02-10T16:14:36ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732020-12-0130671810.22416/1382-4376-2020-30-6-7-18405Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week)V. T. Ivashkin0I. V. Maev1A. S. Trukhmanov2A. A. Sheptulin3V. I. Simanenkov4T. L. Lapina5I. B. Khlynov6N. N. Dekhnich7O. D. Lopina8O. P. Alekseeva9N. V. Korochanskaya10M. F. Osipenko11P. V. Pavlov12S. S. Pirogov13G. N. Tarasova14Yu. P. Uspenskiy15D. N. Andreev16D. E. Rumyantseva17Sechenov First Moscow State University (Sechenov University)Yevdokimov Moscow State University of Medicine and DentistrySechenov First Moscow State University (Sechenov University)Sechenov First Moscow State University (Sechenov University)Mechnikov North-Western State Medical UniversitySechenov First Moscow State University (Sechenov University)Ural State Medical UniversitySmolensk State Medical UniversityLomonosov Moscow State UniversityPrivolzhsky Research Medical UniversityKuban State Medical UniversityNovosibirsk State Medical UniversitySechenov First Moscow State University (Sechenov University)Herzen Moscow Oncology Research Center — Branch of the National Medical Research Radiology CenterRostov State Medical UniversitySaint-Petersburg State Pediatric Medical University; Pavlov First Saint-Petersburg State Medical UniversityYevdokimov Moscow State University of Medicine and DentistrySechenov First Moscow State University (Sechenov University)Aim. Presentation of the Forum “Deprescribing and optimal selection of proton pump inhibitors” held in Moscow on 29 September 2020 during the 26th United Russian Gastroenterology Week.Key points. The Forum was aimed at discussing issues associated with improving the proton pump inhibitor (PPIs) therapy in treatment and prevention of acid-related diseases and upper gastrointestinal tract (GIT) disorders induced by non-steroidal anti-inflammatory drugs (NSAIDs) and antiplatelet medications. Deprescribing is considered to be an effective strategy of a motivated reduction of the PPI dosage, duration of therapy and the patient’s transfer from a regular to on-demand intake regimen. The choice of PPI may condition an optimal therapy for acid-related diseases.Conclusion. PPIs prevail in therapies for acid-related diseases and NSAID-induced upper GIT lesions. PPI deprescribing should be a strategy of choice if medically indicated. A non-enzymatic metabolism, high acid suppression, stable antisecretory effect from day 1 of therapy and cytoprotective action justify the application of rabeprazole (Pariet®) for optimising therapies for acid-related diseases and implementing the deprescribing strategy.https://www.gastro-j.ru/jour/article/view/535acid-related diseasesproton pump inhibitorsrabeprazoledeprescribing |
| spellingShingle | V. T. Ivashkin I. V. Maev A. S. Trukhmanov A. A. Sheptulin V. I. Simanenkov T. L. Lapina I. B. Khlynov N. N. Dekhnich O. D. Lopina O. P. Alekseeva N. V. Korochanskaya M. F. Osipenko P. V. Pavlov S. S. Pirogov G. N. Tarasova Yu. P. Uspenskiy D. N. Andreev D. E. Rumyantseva Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) Российский журнал гастроэнтерологии, гепатологии, колопроктологии acid-related diseases proton pump inhibitors rabeprazole deprescribing |
| title | Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) |
| title_full | Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) |
| title_fullStr | Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) |
| title_full_unstemmed | Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) |
| title_short | Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) |
| title_sort | deprescribing and optimal selection of proton pump inhibitors contributions of the 26th united russian gastroenterology week |
| topic | acid-related diseases proton pump inhibitors rabeprazole deprescribing |
| url | https://www.gastro-j.ru/jour/article/view/535 |
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