COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS
The article considers variability of antigen protein E of different tick-borne encephalitis (TBE) strains at the level of physicochemical properties of amino acid residues. The authors evaluated variety of properties of protein amino acids involved in antigen-antibody interaction. 180 variants of TB...
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2014-11-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/1843 |
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| _version_ | 1849251698025955328 |
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| author | Yu. S. Bukin Yu. P. Dzhioev I. V. Kozlova D. .. Ruzek V. I. Zlobin |
| author_facet | Yu. S. Bukin Yu. P. Dzhioev I. V. Kozlova D. .. Ruzek V. I. Zlobin |
| author_sort | Yu. S. Bukin |
| collection | DOAJ |
| description | The article considers variability of antigen protein E of different tick-borne encephalitis (TBE) strains at the level of physicochemical properties of amino acid residues. The authors evaluated variety of properties of protein amino acids involved in antigen-antibody interaction. 180 variants of TBEVE protein in database NCB1 were detected, differing in physical and chemical properties of amino acid residues. This implies that natural variants of TBEV strains can potentially be detected, that escaped from the immune response induced by standard vaccine. |
| format | Article |
| id | doaj-art-7709164f6af243f6bd74489a129d2825 |
| institution | Kabale University |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| publishDate | 2014-11-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj-art-7709164f6af243f6bd74489a129d28252025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962014-11-010684881789COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUSYu. S. Bukin0Yu. P. Dzhioev1I. V. Kozlova2D. .. Ruzek3V. I. Zlobin4Limnological Institute SB RAS; National Research Irkutsk State Technical UniversityScientific Center of Family Health Problems and Human Reproduction; Irkutsk State Medical UniversityScientific Center of Family Health Problems and Human ReproductionInstitute of Parasitology, Ceske Budejovice, Czech Republic; Veterinary InstituteIrkutsk State Medical UniversityThe article considers variability of antigen protein E of different tick-borne encephalitis (TBE) strains at the level of physicochemical properties of amino acid residues. The authors evaluated variety of properties of protein amino acids involved in antigen-antibody interaction. 180 variants of TBEVE protein in database NCB1 were detected, differing in physical and chemical properties of amino acid residues. This implies that natural variants of TBEV strains can potentially be detected, that escaped from the immune response induced by standard vaccine.https://www.actabiomedica.ru/jour/article/view/1843tick-borne encephalitis virusenvelope protein etbe vaccineproteomic |
| spellingShingle | Yu. S. Bukin Yu. P. Dzhioev I. V. Kozlova D. .. Ruzek V. I. Zlobin COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS Acta Biomedica Scientifica tick-borne encephalitis virus envelope protein e tbe vaccine proteomic |
| title | COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
| title_full | COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
| title_fullStr | COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
| title_full_unstemmed | COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
| title_short | COMPARATIVE ANALYSIS OF THE PHYSICOCHEMICAL PROPERTIES OF AMINO ACID RESIDUES WITHIN THE VARIOUS EMBODIMENTS OF THE ENVELOPE PROTEIN E TICK-BORNE ENCEPHALITIS VIRUS |
| title_sort | comparative analysis of the physicochemical properties of amino acid residues within the various embodiments of the envelope protein e tick borne encephalitis virus |
| topic | tick-borne encephalitis virus envelope protein e tbe vaccine proteomic |
| url | https://www.actabiomedica.ru/jour/article/view/1843 |
| work_keys_str_mv | AT yusbukin comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT yupdzhioev comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT ivkozlova comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT druzek comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus AT vizlobin comparativeanalysisofthephysicochemicalpropertiesofaminoacidresidueswithinthevariousembodimentsoftheenvelopeproteinetickborneencephalitisvirus |