Investigations on Binding Pattern of Kinase Inhibitors with PPARγ: Molecular Docking, Molecular Dynamic Simulations, and Free Energy Calculation Studies

Investigations on Binding Pattern of Kinase Inhibitors with PPARγ: Molecular Docking, Molecular Dynamic Simulations, and Free Energy Calculation Studies

Peroxisome proliferator-activated receptor gamma (PPARγ) is a potential target for the treatment of several disorders. In view of several FDA approved kinase inhibitors, in the current study, we have investigated the interaction of selected kinase inhibitors with PPARγ using computational modeling,...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohit Mazumder, Prija Ponnan, Umashankar Das, Samudrala Gourinath, Haseeb Ahmad Khan, Jian Yang, Meena Kishore Sakharkar
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2017/6397836
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items