Neurological, functional, and quality of life outcomes following combined mesenchymal stem cell and Schwann cell therapy in spinal cord injury: a 9-year experience

Neurological, functional, and quality of life outcomes following combined mesenchymal stem cell and Schwann cell therapy in spinal cord injury: a 9-year experience

Abstract Background Spinal cord injury (SCI) often results in severe disabilities and significant socioeconomic burdens. Objective This study aimed to evaluate the effects and safety of co-transplantation of autologous bone marrow-derived mesenchymal stem cells (MSCs) and Schwann cells (SCs) via the...

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Main Authors: Mohammadhosein Akhlaghpasand, Roozbeh Tavanaei, Maede Hosseinpoor, Maryam Golmohammadi, Ida Mohammadi, Amir Ghaffari Jolfayi, Melika Hosseinpour, Bardia Hajikarimloo, Kaveh Oraii Yazdani, Alireza Zali, Saeed Oraee-Yazdani
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Stem Cell Research & Therapy
Subjects:
Spinal cord injury
Stem cell therapy
Schwann cell
Mesenchymal stem cell
Online Access:https://doi.org/10.1186/s13287-025-04312-7
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