Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 Pandemic

Objective: Prior to the 2020 Coronavirus disease 2019 (COVID-19) pandemic, breast cancer (BC) was already a major healthcare concern globally, including in South Africa (SA). The pandemic forced adjustments in BC management and may have also impacted BC presentation characteristics due to social beh...

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Main Authors: Nazreen Kara, Dominic da Costa, Ella Dougherty, Amina Mahomed, Cassandra Mbanje, Carol-Ann Benn, Dominic van Loggerenberg
Format: Article
Language:English
Published: Galenos Publishing House 2025-04-01
Series:European Journal of Breast Health
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Online Access:https://www.eurjbreasthealth.com/articles/differences-in-age-stage-and-biology-of-breast-cancer-presentations-at-a-private-breast-unit-in-johannesburg-before-and-during-the-covid-19-pandemic/doi/ejbh.galenos.2025.2024-12-2
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author Nazreen Kara
Dominic da Costa
Ella Dougherty
Amina Mahomed
Cassandra Mbanje
Carol-Ann Benn
Dominic van Loggerenberg
author_facet Nazreen Kara
Dominic da Costa
Ella Dougherty
Amina Mahomed
Cassandra Mbanje
Carol-Ann Benn
Dominic van Loggerenberg
author_sort Nazreen Kara
collection DOAJ
description Objective: Prior to the 2020 Coronavirus disease 2019 (COVID-19) pandemic, breast cancer (BC) was already a major healthcare concern globally, including in South Africa (SA). The pandemic forced adjustments in BC management and may have also impacted BC presentation characteristics due to social behavior changes. The aim of this study was to describe BC presentations before and during the COVID-19 pandemic at a single facility in SA. Materials and Methods. A retrospective record review was conducted to compare BC presentations before and during the COVID-19 pandemic. The “before” period spanned 11 January 2019 to 31 March 2020 and the “during” period spanned 1 April 2020 to 20 December 2021. The variables analysed included patient age, BC stage at presentation, and tumor biology. Results: A total of 731 patients were seen in the “before” period, and 636 in the “during” period. While there was a significant (p<0.0001) decrease in the mean number of patients who presented to the unit per month during the pandemic, no significant differences were observed in age, BC stage at presentation, or tumor biology between the two study periods. Conclusion: Despite a significant reduction in new BC cases during the COVID-19 pandemic in SA, patient age, BC stage, and tumor biology remained unchanged. The rapid implementation of digital tools for healthcare management is likely to have played an important role in maintaining patient access to care.
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spelling doaj-art-76f600a260214fd78d57b496b1d2b5ea2025-08-20T02:48:24ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312025-04-0121213213610.4274/ejbh.galenos.2025.2024-12-2Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 PandemicNazreen Kara0https://orcid.org/0000-0002-5712-7307Dominic da Costa1https://orcid.org/0009-0009-3708-8126Ella Dougherty2https://orcid.org/0009-0003-5057-7326Amina Mahomed3https://orcid.org/0009-0006-8392-3207Cassandra Mbanje4https://orcid.org/0000-0003-0509-9292Carol-Ann Benn5https://orcid.org/0000-0002-4777-4316Dominic van Loggerenberg6https://orcid.org/0000-0002-5130-5651Clinic of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, South AfricaDepartment of Obstetrics and Gynecology, Chris Hani Baragwanath Academic Hospital, Johannesburg, South AfricaDepartment of Surgery, Chris Hani Baragwanath Academic Hospital, Johannesburg, South AfricaDepartment of Surgery, Chris Hani Baragwanath Academic Hospital, Johannesburg, South AfricaDepartment of Population Health, Oxford University Faculty of Medicine, Oxford, United KingdomDepartment of Breast Surgery, Netcare Milpark Breast Care Centre of Excellence, Johannesburg, South AfricaDepartment of Breast Surgery, Netcare Milpark Breast Care Centre of Excellence, Johannesburg, South AfricaObjective: Prior to the 2020 Coronavirus disease 2019 (COVID-19) pandemic, breast cancer (BC) was already a major healthcare concern globally, including in South Africa (SA). The pandemic forced adjustments in BC management and may have also impacted BC presentation characteristics due to social behavior changes. The aim of this study was to describe BC presentations before and during the COVID-19 pandemic at a single facility in SA. Materials and Methods. A retrospective record review was conducted to compare BC presentations before and during the COVID-19 pandemic. The “before” period spanned 11 January 2019 to 31 March 2020 and the “during” period spanned 1 April 2020 to 20 December 2021. The variables analysed included patient age, BC stage at presentation, and tumor biology. Results: A total of 731 patients were seen in the “before” period, and 636 in the “during” period. While there was a significant (p<0.0001) decrease in the mean number of patients who presented to the unit per month during the pandemic, no significant differences were observed in age, BC stage at presentation, or tumor biology between the two study periods. Conclusion: Despite a significant reduction in new BC cases during the COVID-19 pandemic in SA, patient age, BC stage, and tumor biology remained unchanged. The rapid implementation of digital tools for healthcare management is likely to have played an important role in maintaining patient access to care.https://www.eurjbreasthealth.com/articles/differences-in-age-stage-and-biology-of-breast-cancer-presentations-at-a-private-breast-unit-in-johannesburg-before-and-during-the-covid-19-pandemic/doi/ejbh.galenos.2025.2024-12-2breast cancerpandemicagestagebiologypresentation
spellingShingle Nazreen Kara
Dominic da Costa
Ella Dougherty
Amina Mahomed
Cassandra Mbanje
Carol-Ann Benn
Dominic van Loggerenberg
Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 Pandemic
European Journal of Breast Health
breast cancer
pandemic
age
stage
biology
presentation
title Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 Pandemic
title_full Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 Pandemic
title_fullStr Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 Pandemic
title_full_unstemmed Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 Pandemic
title_short Differences in Age, Stage and Biology of Breast Cancer Presentations at A Private Breast Unit in Johannesburg Before and During The COVID-19 Pandemic
title_sort differences in age stage and biology of breast cancer presentations at a private breast unit in johannesburg before and during the covid 19 pandemic
topic breast cancer
pandemic
age
stage
biology
presentation
url https://www.eurjbreasthealth.com/articles/differences-in-age-stage-and-biology-of-breast-cancer-presentations-at-a-private-breast-unit-in-johannesburg-before-and-during-the-covid-19-pandemic/doi/ejbh.galenos.2025.2024-12-2
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