Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings
The recent revolution in digital technologies and information processing methods present important opportunities to transform the way optical imaging is performed, particularly toward improving the throughput of microscopes while at the same time reducing their relative cost and complexity. Lensfree...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.3233/ACP-2012-0057 |
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| _version_ | 1850218836959166464 |
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| author | Serhan O. Isikman Alon Greenbaum Myungjun Lee Waheb Bishara Onur Mudanyali Ting-Wei Su Aydogan Ozcan |
| author_facet | Serhan O. Isikman Alon Greenbaum Myungjun Lee Waheb Bishara Onur Mudanyali Ting-Wei Su Aydogan Ozcan |
| author_sort | Serhan O. Isikman |
| collection | DOAJ |
| description | The recent revolution in digital technologies and information processing methods present important opportunities to transform the way optical imaging is performed, particularly toward improving the throughput of microscopes while at the same time reducing their relative cost and complexity. Lensfree computational microscopy is rapidly emerging toward this end, and by discarding lenses and other bulky optical components of conventional imaging systems, and relying on digital computation instead, it can achieve both reflection and transmission mode microscopy over a large field-of-view within compact, cost-effective and mechanically robust architectures. Such high throughput and miniaturized imaging devices can provide a complementary toolset for telemedicine applications and point-of-care diagnostics by facilitating complex and critical tasks such as cytometry and microscopic analysis of e.g., blood smears, Pap tests and tissue samples. In this article, the basics of these lensfree microscopy modalities will be reviewed, and their clinically relevant applications will be discussed. |
| format | Article |
| id | doaj-art-76f0a72dc9524ce189a17a0e37ba9341 |
| institution | OA Journals |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-76f0a72dc9524ce189a17a0e37ba93412025-08-20T02:07:35ZengWileyAnalytical Cellular Pathology2210-71772210-71852012-01-0135422924710.3233/ACP-2012-0057Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource SettingsSerhan O. Isikman0Alon Greenbaum1Myungjun Lee2Waheb Bishara3Onur Mudanyali4Ting-Wei Su5Aydogan Ozcan6Electrical Engineering Department, University of California, Los Angeles, CA, USAElectrical Engineering Department, University of California, Los Angeles, CA, USAElectrical Engineering Department, University of California, Los Angeles, CA, USAElectrical Engineering Department, University of California, Los Angeles, CA, USAElectrical Engineering Department, University of California, Los Angeles, CA, USAElectrical Engineering Department, University of California, Los Angeles, CA, USAElectrical Engineering Department, University of California, Los Angeles, CA, USAThe recent revolution in digital technologies and information processing methods present important opportunities to transform the way optical imaging is performed, particularly toward improving the throughput of microscopes while at the same time reducing their relative cost and complexity. Lensfree computational microscopy is rapidly emerging toward this end, and by discarding lenses and other bulky optical components of conventional imaging systems, and relying on digital computation instead, it can achieve both reflection and transmission mode microscopy over a large field-of-view within compact, cost-effective and mechanically robust architectures. Such high throughput and miniaturized imaging devices can provide a complementary toolset for telemedicine applications and point-of-care diagnostics by facilitating complex and critical tasks such as cytometry and microscopic analysis of e.g., blood smears, Pap tests and tissue samples. In this article, the basics of these lensfree microscopy modalities will be reviewed, and their clinically relevant applications will be discussed.http://dx.doi.org/10.3233/ACP-2012-0057 |
| spellingShingle | Serhan O. Isikman Alon Greenbaum Myungjun Lee Waheb Bishara Onur Mudanyali Ting-Wei Su Aydogan Ozcan Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings Analytical Cellular Pathology |
| title | Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings |
| title_full | Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings |
| title_fullStr | Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings |
| title_full_unstemmed | Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings |
| title_short | Modern Trends in Imaging VIII: Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings |
| title_sort | modern trends in imaging viii lensfree computational microscopy tools for cell and tissue imaging at the point of care and in low resource settings |
| url | http://dx.doi.org/10.3233/ACP-2012-0057 |
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