Gingival Stem Cell‐Conditioned Media and Low‐Level Laser Therapy Enhance Periodontal Ligament Stem Cells Function by Upregulating Wnt and TGF‐β Pathway Components: An In Vitro Study

Gingival Stem Cell‐Conditioned Media and Low‐Level Laser Therapy Enhance Periodontal Ligament Stem Cells Function by Upregulating Wnt and TGF‐β Pathway Components: An In Vitro Study

ABSTRACT Objectives This study investigated the synergistic effects of gingival stem cell conditioned media (GSC‐CM) and low‐level laser therapy (LLLT) on stimulating PDLSCs, explicitly focusing on the molecular basis of enhancing the Wnt and TGF‐β signaling pathways. Material and Methods PDLSCs wer...

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Bibliographic Details
Main Authors: Mohammed Y. Aljabri, Yaser A. Alhazmi, Salah A. Elsayyad, Shehabeldin M. Saber, Mohamed Shamel
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Clinical and Experimental Dental Research
Subjects:
gingival stem cell‐conditioned media
low‐level laser therapy
osteogenic differentiation
PDLSCs
periodontal regeneration
TGF‐β signaling pathway
Online Access:https://doi.org/10.1002/cre2.70151
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