Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur

Tumor-induced hypophosphatemic osteomalacia is a rare disease and its diagnosis presents certain difficulties. This is primarily due to small tumor size and to the absence of local clinical symptoms. Adult-onset newly diagnosed hypophosphatemia concurrent with hyperphosphaturia is a sign of tumor-in...

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Main Authors: S. S. Rodionova, A. I. Snetkov, A. D. Akinshina, I. V. Bulycheva, A. N. Torgashin, T. A. Grebennikova, Zh. E. Belaya, Е. M. Agafonova, N. V. Toroptsova, O. A. Nikitinskaya
Format: Article
Language:Russian
Published: IMA PRESS LLC 2019-12-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/2810
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author S. S. Rodionova
A. I. Snetkov
A. D. Akinshina
I. V. Bulycheva
A. N. Torgashin
T. A. Grebennikova
Zh. E. Belaya
Е. M. Agafonova
N. V. Toroptsova
O. A. Nikitinskaya
author_facet S. S. Rodionova
A. I. Snetkov
A. D. Akinshina
I. V. Bulycheva
A. N. Torgashin
T. A. Grebennikova
Zh. E. Belaya
Е. M. Agafonova
N. V. Toroptsova
O. A. Nikitinskaya
author_sort S. S. Rodionova
collection DOAJ
description Tumor-induced hypophosphatemic osteomalacia is a rare disease and its diagnosis presents certain difficulties. This is primarily due to small tumor size and to the absence of local clinical symptoms. Adult-onset newly diagnosed hypophosphatemia concurrent with hyperphosphaturia is a sign of tumor-induced hypophosphatemic osteomalacia. The paper describes a female patient with fibroblast growth factor 23-secreting tumor of the upper third of the femur. After tumor removal, pharmacological treatment involves prescribing calcium supplements and active vitamin D metabolite until normal bone mineral density is restored.
format Article
id doaj-art-76e817c0e90e40e293169d3236594388
institution DOAJ
issn 1995-4484
1995-4492
language Russian
publishDate 2019-12-01
publisher IMA PRESS LLC
record_format Article
series Научно-практическая ревматология
spelling doaj-art-76e817c0e90e40e293169d32365943882025-08-20T03:22:12ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922019-12-0157670871210.14412/1995-4484-2019-708-7122559Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femurS. S. Rodionova0A. I. Snetkov1A. D. Akinshina2I. V. Bulycheva3A. N. Torgashin4T. A. Grebennikova5Zh. E. Belaya6Е. M. Agafonova7N. V. Toroptsova8O. A. Nikitinskaya9N.N. Priorov National Medical Research Center of Traumatology and Orthopedics, Ministry of Health of RussiaN.N. Priorov National Medical Research Center of Traumatology and Orthopedics, Ministry of Health of RussiaN.N. Priorov National Medical Research Center of Traumatology and Orthopedics, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaN.N. Priorov National Medical Research Center of Traumatology and Orthopedics, Ministry of Health of RussiaNational Medical Research Center of Endocrinology, Ministry of Health of RussiaNational Medical Research Center of Endocrinology, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyTumor-induced hypophosphatemic osteomalacia is a rare disease and its diagnosis presents certain difficulties. This is primarily due to small tumor size and to the absence of local clinical symptoms. Adult-onset newly diagnosed hypophosphatemia concurrent with hyperphosphaturia is a sign of tumor-induced hypophosphatemic osteomalacia. The paper describes a female patient with fibroblast growth factor 23-secreting tumor of the upper third of the femur. After tumor removal, pharmacological treatment involves prescribing calcium supplements and active vitamin D metabolite until normal bone mineral density is restored.https://rsp.mediar-press.net/rsp/article/view/2810osteomalaciafibroblast growth factor 23tumorhypophosphatemia, metabolic diseases
spellingShingle S. S. Rodionova
A. I. Snetkov
A. D. Akinshina
I. V. Bulycheva
A. N. Torgashin
T. A. Grebennikova
Zh. E. Belaya
Е. M. Agafonova
N. V. Toroptsova
O. A. Nikitinskaya
Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur
Научно-практическая ревматология
osteomalacia
fibroblast growth factor 23
tumor
hypophosphatemia, metabolic diseases
title Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur
title_full Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur
title_fullStr Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur
title_full_unstemmed Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur
title_short Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur
title_sort hypophosphatemic osteomalacia induced by fgf23 secreting tumor of the left femur
topic osteomalacia
fibroblast growth factor 23
tumor
hypophosphatemia, metabolic diseases
url https://rsp.mediar-press.net/rsp/article/view/2810
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