Hypophosphatemic osteomalacia induced by FGF23-secreting tumor of the left femur

Tumor-induced hypophosphatemic osteomalacia is a rare disease and its diagnosis presents certain difficulties. This is primarily due to small tumor size and to the absence of local clinical symptoms. Adult-onset newly diagnosed hypophosphatemia concurrent with hyperphosphaturia is a sign of tumor-in...

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Main Authors: S. S. Rodionova, A. I. Snetkov, A. D. Akinshina, I. V. Bulycheva, A. N. Torgashin, T. A. Grebennikova, Zh. E. Belaya, Е. M. Agafonova, N. V. Toroptsova, O. A. Nikitinskaya
Format: Article
Language:Russian
Published: IMA PRESS LLC 2019-12-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/2810
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Summary:Tumor-induced hypophosphatemic osteomalacia is a rare disease and its diagnosis presents certain difficulties. This is primarily due to small tumor size and to the absence of local clinical symptoms. Adult-onset newly diagnosed hypophosphatemia concurrent with hyperphosphaturia is a sign of tumor-induced hypophosphatemic osteomalacia. The paper describes a female patient with fibroblast growth factor 23-secreting tumor of the upper third of the femur. After tumor removal, pharmacological treatment involves prescribing calcium supplements and active vitamin D metabolite until normal bone mineral density is restored.
ISSN:1995-4484
1995-4492