A study on determination of an optimized detector for single photon emission computed tomography

The detector is a critical component of the single photon emission computed tomography (SPECT) imaging system for giving accurate information from the exact pattern of radionuclide distribution in the target organ. The SIMIND Monte Carlo program was utilized for the simulation of a Siemen's dua...

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Main Authors: Mohammad Khoshakhlagh, Jalil Islamian, Mohammad Abedi, Babak Mahmoudian, Ali Mardanshahi
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2016-01-01
Series:World Journal of Nuclear Medicine
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.167588
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author Mohammad Khoshakhlagh
Jalil Islamian
Mohammad Abedi
Babak Mahmoudian
Ali Mardanshahi
author_facet Mohammad Khoshakhlagh
Jalil Islamian
Mohammad Abedi
Babak Mahmoudian
Ali Mardanshahi
author_sort Mohammad Khoshakhlagh
collection DOAJ
description The detector is a critical component of the single photon emission computed tomography (SPECT) imaging system for giving accurate information from the exact pattern of radionuclide distribution in the target organ. The SIMIND Monte Carlo program was utilized for the simulation of a Siemen's dual head variable angle SPECT imaging system with a low energy high resolution (LEHR) collimator. The Planar and SPECT scans for a 99mTc point source and a Jaszczak Phantom with the both experiment and simulated systems were prepared and after verification and validation of the simulated system, the similar scans of the phantoms were compared (from the point of view of the images' quality), namely, the simulated system with the detectors including bismuth germanate (BGO), yttrium aluminum garnet (YAG:Ce), Cerium-doped yttrium aluminum garnet (YAG:Ce), yttrium aluminum perovslite (YAP:Ce), lutetium aluminum garnet (LuAG:Ce), cerium activated lanthanum bromide (LaBr3), cadmium zinc telluride (CZT), and sodium iodide activated with thallium [NaI(Tl)]. The parameters of full width at half maximum (FWHM), energy and special resolution, sensitivity, and also the comparison of images' quality by the structural similarity (SSIM) algorithm with the Zhou Wang and Rouse/Hemami methods were analyzed. FWHMs for the crystals were calculated at 13.895, 14.321, 14.310, 14.322, 14.184, and 14.312 keV and the related energy resolutions obtained 9.854, 10.229, 10.221, 10.230, 10.131, and 10.223 %, respectively. Finally, SSIM indexes for comparison of the phantom images were calculated at 0.22172, 0.16326, 0.18135, 0.17301, 0.18412, and 0.20433 as compared to NaI(Tl). The results showed that BGO and LuAG: Ce crystals have high sensitivity and resolution, and better image quality as compared to other scintillation crystals.
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spelling doaj-art-76e4e58f2afb412081ee6ee0b048b12f2025-08-20T02:54:43ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122016-01-011501121710.4103/1450-1147.167588A study on determination of an optimized detector for single photon emission computed tomographyMohammad Khoshakhlagh0Jalil Islamian1Mohammad Abedi2Babak Mahmoudian3Ali Mardanshahi4Immunology Research Center, Tabriz University of Medical Sciences, Sari, IranDepartment of Medical Physics, Faculty of Medicine Tabriz University of Medical Sciences, TabrizDepartment of Radiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IranDepartment of Radiology, Radiotherapy and Nuclear Medicine, Faculty of Medicine, Tabriz University of Medical SciencesDepartment of Radiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IranThe detector is a critical component of the single photon emission computed tomography (SPECT) imaging system for giving accurate information from the exact pattern of radionuclide distribution in the target organ. The SIMIND Monte Carlo program was utilized for the simulation of a Siemen's dual head variable angle SPECT imaging system with a low energy high resolution (LEHR) collimator. The Planar and SPECT scans for a 99mTc point source and a Jaszczak Phantom with the both experiment and simulated systems were prepared and after verification and validation of the simulated system, the similar scans of the phantoms were compared (from the point of view of the images' quality), namely, the simulated system with the detectors including bismuth germanate (BGO), yttrium aluminum garnet (YAG:Ce), Cerium-doped yttrium aluminum garnet (YAG:Ce), yttrium aluminum perovslite (YAP:Ce), lutetium aluminum garnet (LuAG:Ce), cerium activated lanthanum bromide (LaBr3), cadmium zinc telluride (CZT), and sodium iodide activated with thallium [NaI(Tl)]. The parameters of full width at half maximum (FWHM), energy and special resolution, sensitivity, and also the comparison of images' quality by the structural similarity (SSIM) algorithm with the Zhou Wang and Rouse/Hemami methods were analyzed. FWHMs for the crystals were calculated at 13.895, 14.321, 14.310, 14.322, 14.184, and 14.312 keV and the related energy resolutions obtained 9.854, 10.229, 10.221, 10.230, 10.131, and 10.223 %, respectively. Finally, SSIM indexes for comparison of the phantom images were calculated at 0.22172, 0.16326, 0.18135, 0.17301, 0.18412, and 0.20433 as compared to NaI(Tl). The results showed that BGO and LuAG: Ce crystals have high sensitivity and resolution, and better image quality as compared to other scintillation crystals.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.167588gamma detectorjaszczak phantomsimind simulationstructural similarity algorithm
spellingShingle Mohammad Khoshakhlagh
Jalil Islamian
Mohammad Abedi
Babak Mahmoudian
Ali Mardanshahi
A study on determination of an optimized detector for single photon emission computed tomography
World Journal of Nuclear Medicine
gamma detector
jaszczak phantom
simind simulation
structural similarity algorithm
title A study on determination of an optimized detector for single photon emission computed tomography
title_full A study on determination of an optimized detector for single photon emission computed tomography
title_fullStr A study on determination of an optimized detector for single photon emission computed tomography
title_full_unstemmed A study on determination of an optimized detector for single photon emission computed tomography
title_short A study on determination of an optimized detector for single photon emission computed tomography
title_sort study on determination of an optimized detector for single photon emission computed tomography
topic gamma detector
jaszczak phantom
simind simulation
structural similarity algorithm
url http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.167588
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