Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil diet

This study was to investigate the effects of dietary Lactobacillus pentosus (LP) supplementation on the growth performance, serum biochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus) fed with oxidized fish oil. Diet containing 9 % fresh fish oil was used...

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Main Authors: Wenshan Cai, Zhihao Li, Weibin Huang, Menglong Zhou, Hao Liu, Yuanzhi Yang, Beiping Tan, Xiaohui Dong
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S235251342500122X
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author Wenshan Cai
Zhihao Li
Weibin Huang
Menglong Zhou
Hao Liu
Yuanzhi Yang
Beiping Tan
Xiaohui Dong
author_facet Wenshan Cai
Zhihao Li
Weibin Huang
Menglong Zhou
Hao Liu
Yuanzhi Yang
Beiping Tan
Xiaohui Dong
author_sort Wenshan Cai
collection DOAJ
description This study was to investigate the effects of dietary Lactobacillus pentosus (LP) supplementation on the growth performance, serum biochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus) fed with oxidized fish oil. Diet containing 9 % fresh fish oil was used as the positive control group (Group F); diet containing 9 % oxidized fish oil was used as the negative control group (Group O), and 1 × 107cfu/g, 1 × 108cfu/g, and 1 × 109 cfu/g of LP were added to Group O, named Group O+ 7 L, O+ 8 L, and O+ 9 L. The results showed that (1) Growth performance of group F and group O+ 9 L were considerably greater than those of group O (P < 0.05). (2) The total cholesterol (CHOL) and high-density lipoprotein (HDL-C) contents in the serum of group F and group O+ 9 L grouper were considerably greater than those of group O, and the low-density lipoprotein (LDL-C) and malondialdehyde (MDA) contents were considerably less than those of group O (P < 0.05). The alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum of group O were considerably greater than those of group F and group O+ 9 L (P < 0.05). (3) Liver nuclear respiratory factor 2 (nrf2), glutathione peroxidase (gpx), catalase (cat), peroxisome proliferator-activated receptor α (pparα), carnitine palmitoyltransferase1 (cpt1), and phosphatase and tensin homolog (pten) expression were up-regulated, and hepatic kelch-like ECH-associated protein 1 (keap1), and peroxisome proliferator-activated receptor γ (pparγ) expression were down-regulated of LP treated group, compared with group O. The results showed that the addition of 1 × 109 cfu/g LP promoted the decomposition lipid and antioxidant capacity of liver, thereby resisting the damage of oxidized fish oil to grouper.
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spelling doaj-art-76db1d5d6db94276a822a8d1013505282025-08-20T03:45:47ZengElsevierAquaculture Reports2352-51342025-07-014210273610.1016/j.aqrep.2025.102736Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil dietWenshan Cai0Zhihao Li1Weibin Huang2Menglong Zhou3Hao Liu4Yuanzhi Yang5Beiping Tan6Xiaohui Dong7Laboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, China; Key Laboratory of Aquatic, Livestock and Poultry Feed Science and Technology in South China, Ministry of Agriculture, Zhanjiang, Guangdong 524000, ChinaLaboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China; GuangDong Engineering Technology Research Center of Aquatic Animals Precision Nutrition and High Efficiency Feed, Zhanjiang, Guangdong 524088, China; Key Laboratory of Aquatic, Livestock and Poultry Feed Science and Technology in South China, Ministry of Agriculture, Zhanjiang, Guangdong 524000, China; Corresponding author at: Laboratory of Aquatic Nutrition and Feed, College of Fisheries, Guangdong Ocean University, Zhanjiang, Guangdong 524088, China.This study was to investigate the effects of dietary Lactobacillus pentosus (LP) supplementation on the growth performance, serum biochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus) fed with oxidized fish oil. Diet containing 9 % fresh fish oil was used as the positive control group (Group F); diet containing 9 % oxidized fish oil was used as the negative control group (Group O), and 1 × 107cfu/g, 1 × 108cfu/g, and 1 × 109 cfu/g of LP were added to Group O, named Group O+ 7 L, O+ 8 L, and O+ 9 L. The results showed that (1) Growth performance of group F and group O+ 9 L were considerably greater than those of group O (P < 0.05). (2) The total cholesterol (CHOL) and high-density lipoprotein (HDL-C) contents in the serum of group F and group O+ 9 L grouper were considerably greater than those of group O, and the low-density lipoprotein (LDL-C) and malondialdehyde (MDA) contents were considerably less than those of group O (P < 0.05). The alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum of group O were considerably greater than those of group F and group O+ 9 L (P < 0.05). (3) Liver nuclear respiratory factor 2 (nrf2), glutathione peroxidase (gpx), catalase (cat), peroxisome proliferator-activated receptor α (pparα), carnitine palmitoyltransferase1 (cpt1), and phosphatase and tensin homolog (pten) expression were up-regulated, and hepatic kelch-like ECH-associated protein 1 (keap1), and peroxisome proliferator-activated receptor γ (pparγ) expression were down-regulated of LP treated group, compared with group O. The results showed that the addition of 1 × 109 cfu/g LP promoted the decomposition lipid and antioxidant capacity of liver, thereby resisting the damage of oxidized fish oil to grouper.http://www.sciencedirect.com/science/article/pii/S235251342500122X♀ Epinephelus fuscoguttatus × ♂ E. lanceolatusOxidized fish oilLactobacillus pentosusLipid metabolismAntioxidant
spellingShingle Wenshan Cai
Zhihao Li
Weibin Huang
Menglong Zhou
Hao Liu
Yuanzhi Yang
Beiping Tan
Xiaohui Dong
Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil diet
Aquaculture Reports
♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus
Oxidized fish oil
Lactobacillus pentosus
Lipid metabolism
Antioxidant
title Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil diet
title_full Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil diet
title_fullStr Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil diet
title_full_unstemmed Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil diet
title_short Effects of dietary Lactobacillus pentosus supplementation on growth performance, serumbiochemistry and liver function of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil diet
title_sort effects of dietary lactobacillus pentosus supplementation on growth performance serumbiochemistry and liver function of hybrid grouper ♀ epinephelus fuscoguttatus ♂ epinephelus lanceolatus fed with oxidized fish oil diet
topic ♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus
Oxidized fish oil
Lactobacillus pentosus
Lipid metabolism
Antioxidant
url http://www.sciencedirect.com/science/article/pii/S235251342500122X
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