Autologous precision-cut lung slice co-culture models for studying macrophage-driven fibrosis
Precision-cut lung slices (PCLS) are commonly used as an ex vivo model to study lung fibrosis; however, traditional models lack immune cell infiltration, including the recruitment of monocytes and macrophages, which are critical for inflammation and fibrosis. To address this limitation, we developed...
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Main Authors: | So-Yi Chang, Wen-Hsin Chang, David C. Yang, Qi-Sheng Hong, Ssu-Wei Hsu, Reen Wu, Ching-Hsien Chen |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-01-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2025.1526787/full |
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