Protective Effects of Oridonin on Acute Liver Injury via Impeding Posttranslational Modifications of Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) in the Toll-Like Receptor 4 (TLR4) Signaling Pathway
Objective. Recent researches have demonstrated that inflammation-related diseases are effectively regulated by posttranslational modifications (PTMs) including phosphorylation and acetylation. Our previous study found a new acetyltransferase inhibitor, oridonin, which had a protective effect on acut...
Saved in:
| Main Authors: | Min Shi, Yilin Deng, Heguo Yu, Ling Xu, Cuicui Shi, Jiong Chen, Guangming Li, Yiqi Du, Yu-gang Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2019/7634761 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis
by: Chao Yan, et al.
Published: (2015-10-01) -
Activation of chicken macrophages by isomalto/malto-polysaccharide (IMMP) is facilitated by toll-like receptor 4 (TLR4)
by: Adil Ijaz, et al.
Published: (2025-11-01) -
Association of Toll-like Receptor 4 (TLR4) Gene Polymorphism with Multiple Sclerosis (MS) in Iranian Patients
by: Abdolreza Sotoodeh Jahromi, et al.
Published: (2024-01-01) -
The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets.
by: Humaira Rasheed, et al.
Published: (2016-01-01) -
Characterization of Toll-Like Receptor-4 (TLR-4) in the Spleen and Thymus of Swiss Albino Mice and Its Modulation in Experimental Endotoxemia
by: Chandrayee Ghosh, et al.
Published: (2015-01-01)