PLIN5 contributes to lipophagy of hepatic stellate cells induced by inorganic arsenic

PLIN5 contributes to lipophagy of hepatic stellate cells induced by inorganic arsenic

Arsenic exposure triggers the activation of hepatic stellate cells (HSCs), resulting in liver fibrosis (LF). A significant decrease in lipid droplets marks the activation of HSCs. However, the exact underlying molecular mechanism remains elusive. Lipophagy, a specialized form of selective autophagy,...

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Bibliographic Details
Main Authors: Haomiao Li, Xuri Xie, Tianming Qiu, Jingyuan Zhang, Jie Bai, Guang Yang, Ningning Wang, Xiaofeng Yao, Xiance Sun
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Arsenic
Perilipin 5
Lipophagy
HSCs
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324016233
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