Exploring social impairment in those with opioid use disorder: linking impulsivity, childhood trauma, and the prefrontal cortex

Exploring social impairment in those with opioid use disorder: linking impulsivity, childhood trauma, and the prefrontal cortex

Abstract Background Challenges with social functioning, which is a hallmark of opioid use disorder (OUD), are a drawback in treatment adherence and maintenance. Yet, little research has explored the underlying mechanisms of this impairment. Impulsivity and corresponding neural alterations may be at...

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Bibliographic Details
Main Authors: Thais Costa Macedo de Arruda, Laura Sinko, Paul Regier, Altona Tufanoglu, Adrian Curtin, Anne M. Teitelman, Hasan Ayaz, Peter F. Cronholm, Anna Rose Childress
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Psychiatry
Subjects:
Opioid use disorder
Social functioning
Impulsivity
Childhood trauma
Prefrontal cortex
Brain
Online Access:https://doi.org/10.1186/s12888-025-06503-1
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