BuDDI: Bulk Deconvolution with Domain Invariance to predict cell-type-specific perturbations from bulk.
While single-cell experiments provide deep cellular resolution within a single sample, some single-cell experiments are inherently more challenging than bulk experiments due to dissociation difficulties, cost, or limited tissue availability. This creates a situation where we have deep cellular profi...
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Main Authors: | Natalie R Davidson, Fan Zhang, Casey S Greene |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-01-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1012742 |
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