Hybrid EMT Phenotype and Cell Membrane Tension Promote Colorectal Cancer Resistance to Ferroptosis

Hybrid EMT Phenotype and Cell Membrane Tension Promote Colorectal Cancer Resistance to Ferroptosis

Abstract Intratumoral heterogeneity, including epithelial–mesenchymal transition (EMT), is one major cause of therapeutic resistance. The induction of ferroptosis, an iron‐dependent death, has the potential in overcoming this resistance to traditional treatment modalities. However, the roles of dist...

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Bibliographic Details
Main Authors: Xiaowei Wei, Yutong Ge, Yaolin Zheng, Sunyan Zhao, Yuhan Zhou, Yuhan Chang, Nuofan Wang, Xiumei Wang, Juan Zhang, Xuanchang Zhang, Liqiao Hu, Youhua Tan, Qiong Jia
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
colorectal cancer
ferroptosis
hybrid EMT
membrane tension
physical environment
Online Access:https://doi.org/10.1002/advs.202413882
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