Amikacin use in critically ill patients requiring renal replacement therapy: the AMIDIAL-ICU study

Amikacin use in critically ill patients requiring renal replacement therapy: the AMIDIAL-ICU study

Abstract Background Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is common in intensive care units (ICUs), yet optimal amikacin dosing in this context remains poorly understood. Methods We conducted a prospective observational study across 18 French hospitals from April 2020 t...

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Main Authors: Vincent Dupont, Bruno Mourvillier, Coralie Barbe, Vincent Legros, Mathieu Jozwiak, Hamid Merdji, Claire Dupuis, Hadrien Winiszewski, Antoine Marchalot, Guillaume Lacave, Mathilde Neuville, Anne Sagnier, François Barbier, Carine Thivilier, Stéphanie Ruiz, Roland Smonig, Jeremy Rosman, Laurent Argaud, Steven Grangé, Benjamine Sarton, Patrick Chillet, Guillaume Voiriot, Lukshe Kanagaratnam, Zoubir Djerada
Format: Article
Language:English
Published: SpringerOpen 2025-03-01
Series:Annals of Intensive Care
Subjects:
Amikacin
Aminoglycoside
Renal replacement therapy
Intensive care unit
Pharmacokinetic
Online Access:https://doi.org/10.1186/s13613-025-01461-z
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