Large clones of clonal hematopoiesis affect outcome in mantle cell lymphoma: results from the FIL MCL0208 clinical trial

Large clones of clonal hematopoiesis affect outcome in mantle cell lymphoma: results from the FIL MCL0208 clinical trial

Abstract: Although recent evidence suggests that myeloid clonal hematopoiesis (M-CH) may influence lymphoma clinical outcome, its impact in mantle cell lymphoma (MCL) remains unclear. Here, we report a comprehensive next-generation sequencing–based analysis of the M-CH mutational landscape at baseli...

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Main Authors: Simone Ragaini, Anna Galli, Elisa Genuardi, Martina Gandossini, Beatrice Alessandria, Aurora Maria Civita, Andrea Evangelista, Enrico Amaducci, Vittorio Stefoni, Federica Cavallo, Filippo Ballerini, Benedetta Puccini, Daniele Vallisa, Mariagrazia Michieli, Anna Pascarella, Angelo Palmas, Caterina Patti, Elisa Lucchini, Maria Grazia Careddu, Michele Merli, Massimiliano Postorino, Carola Boccomini, Monica Balzarotti, Vittorio Ruggero Zilioli, Maria Gomes da Silva, Benedetto Bruno, Ettore Rizzo, Marco Ladetto, Luca Malcovati, Simone Ferrero
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925000175
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