Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review

Introduction The application of artificial intelligence (AI) technologies as a diagnostic aid in healthcare is increasing. Benefits include applications to improve health systems, such as rapid and accurate interpretation of medical images. This may improve the performance of diagnostic, prognostic...

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Main Authors: Natalie S Blencowe, Neil J Smart, George E Fowler, Rhiannon C Macefield, Conor Hardacre, Mark P Callaway
Format: Article
Language:English
Published: BMJ Publishing Group 2021-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/10/e054411.full
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author Natalie S Blencowe
Neil J Smart
George E Fowler
Rhiannon C Macefield
Conor Hardacre
Mark P Callaway
author_facet Natalie S Blencowe
Neil J Smart
George E Fowler
Rhiannon C Macefield
Conor Hardacre
Mark P Callaway
author_sort Natalie S Blencowe
collection DOAJ
description Introduction The application of artificial intelligence (AI) technologies as a diagnostic aid in healthcare is increasing. Benefits include applications to improve health systems, such as rapid and accurate interpretation of medical images. This may improve the performance of diagnostic, prognostic and management decisions. While a large amount of work has been undertaken discussing the role of AI little is understood regarding the performance of such applications in the clinical setting. This systematic review aims to critically appraise the diagnostic performance of AI algorithms to identify disease from cross-sectional radiological images of the abdominopelvic cavity, to identify current limitations and inform future research.Methods and analysis A systematic search will be conducted on Medline, EMBASE and the Cochrane Central Register of Controlled Trials to identify relevant studies. Primary studies where AI-based technologies have been used as a diagnostic aid in cross-sectional radiological images of the abdominopelvic cavity will be included. Diagnostic accuracy of AI models, including reported sensitivity, specificity, predictive values, likelihood ratios and the area under the receiver operating characteristic curve will be examined and compared with standard practice. Risk of bias of included studies will be assessed using the QUADAS-2 tool. Findings will be reported according to the Synthesis Without Meta-analysis guidelines.Ethics and dissemination No ethical approval is required as primary data will not be collected. The results will inform further research studies in this field. Findings will be disseminated at relevant conferences, on social media and published in a peer-reviewed journal.PROSPERO registration number CRD42021237249.
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spelling doaj-art-768b8a9d71ce48ce8bfe86e8f86188252025-08-20T02:23:53ZengBMJ Publishing GroupBMJ Open2044-60552021-10-01111010.1136/bmjopen-2021-054411Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic reviewNatalie S Blencowe0Neil J Smart1George E Fowler2Rhiannon C Macefield3Conor Hardacre4Mark P Callaway5National Institute for Health Research Bristol Biomedical Research Centre Surgical and Orthopaedic Innovation Theme, Bristol Centre for Surgical Research, Bristol Medical School, University of Bristol Medical School, Bristol, UKExeter Surgical Health Services Research Unit (HeSRU), Royal Devon and Exeter NHS Foundation Trust, Exeter, UKCentre for Surgical Research, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UKNational Institute for Health and Care Research Bristol Biomedical Research Centre, Bristol Centre for Surgical Research, Bristol Medical School: Population Health Sciences, University of Bristol, Bristol, UKfifth year medical studentDepartment of Clinical Radiology, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, UKIntroduction The application of artificial intelligence (AI) technologies as a diagnostic aid in healthcare is increasing. Benefits include applications to improve health systems, such as rapid and accurate interpretation of medical images. This may improve the performance of diagnostic, prognostic and management decisions. While a large amount of work has been undertaken discussing the role of AI little is understood regarding the performance of such applications in the clinical setting. This systematic review aims to critically appraise the diagnostic performance of AI algorithms to identify disease from cross-sectional radiological images of the abdominopelvic cavity, to identify current limitations and inform future research.Methods and analysis A systematic search will be conducted on Medline, EMBASE and the Cochrane Central Register of Controlled Trials to identify relevant studies. Primary studies where AI-based technologies have been used as a diagnostic aid in cross-sectional radiological images of the abdominopelvic cavity will be included. Diagnostic accuracy of AI models, including reported sensitivity, specificity, predictive values, likelihood ratios and the area under the receiver operating characteristic curve will be examined and compared with standard practice. Risk of bias of included studies will be assessed using the QUADAS-2 tool. Findings will be reported according to the Synthesis Without Meta-analysis guidelines.Ethics and dissemination No ethical approval is required as primary data will not be collected. The results will inform further research studies in this field. Findings will be disseminated at relevant conferences, on social media and published in a peer-reviewed journal.PROSPERO registration number CRD42021237249.https://bmjopen.bmj.com/content/11/10/e054411.full
spellingShingle Natalie S Blencowe
Neil J Smart
George E Fowler
Rhiannon C Macefield
Conor Hardacre
Mark P Callaway
Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review
BMJ Open
title Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review
title_full Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review
title_fullStr Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review
title_full_unstemmed Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review
title_short Artificial intelligence as a diagnostic aid in cross-sectional radiological imaging of the abdominopelvic cavity: a protocol for a systematic review
title_sort artificial intelligence as a diagnostic aid in cross sectional radiological imaging of the abdominopelvic cavity a protocol for a systematic review
url https://bmjopen.bmj.com/content/11/10/e054411.full
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