EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME
The article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2016-11-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1677 |
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| _version_ | 1850023718294650880 |
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| author | Tatyana V. Sleptsova Еkaterina I. Alexeeva Тatyana М. Bzarova Kirill V. Savostyanov Аlexander A. Pushkov Kseniya B. Isaeva Rina V. Denisova Оlga L. Lomakina |
| author_facet | Tatyana V. Sleptsova Еkaterina I. Alexeeva Тatyana М. Bzarova Kirill V. Savostyanov Аlexander A. Pushkov Kseniya B. Isaeva Rina V. Denisova Оlga L. Lomakina |
| author_sort | Tatyana V. Sleptsova |
| collection | DOAJ |
| description | The article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action mechanisms. After 8 weeks of canakinumab therapy, systemic manifestations were cropped, and laboratory parameters of the disease activity were normalized. During the entire care period (12 months), neither serious adverse events nor increased incidence of acute respiratory infections have been reported. |
| format | Article |
| id | doaj-art-7677bc8142954b3b97092bf87c2fc41c |
| institution | DOAJ |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2016-11-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-7677bc8142954b3b97092bf87c2fc41c2025-08-20T03:01:18Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352016-11-0115552252610.15690/vsp.v15i5.16271634EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROMETatyana V. Sleptsova0Еkaterina I. Alexeeva1Тatyana М. Bzarova2Kirill V. Savostyanov3Аlexander A. Pushkov4Kseniya B. Isaeva5Rina V. Denisova6Оlga L. Lomakina7Scientific Center of Children’s HealthScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityScientific Center of Children’s HealthScientific Center of Children’s HealthScientific Center of Children’s HealthScientific Center of Children’s HealthScientific Center of Children’s HealthThe article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action mechanisms. After 8 weeks of canakinumab therapy, systemic manifestations were cropped, and laboratory parameters of the disease activity were normalized. During the entire care period (12 months), neither serious adverse events nor increased incidence of acute respiratory infections have been reported.https://vsp.spr-journal.ru/jour/article/view/1677childrenautoinflammatory syndromecanakinumabclinical case |
| spellingShingle | Tatyana V. Sleptsova Еkaterina I. Alexeeva Тatyana М. Bzarova Kirill V. Savostyanov Аlexander A. Pushkov Kseniya B. Isaeva Rina V. Denisova Оlga L. Lomakina EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME Вопросы современной педиатрии children autoinflammatory syndrome canakinumab clinical case |
| title | EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_full | EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_fullStr | EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_full_unstemmed | EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_short | EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_sort | experience of the successful canakinumab treatment of a patient with undifferentiated autoinflammatory syndrome |
| topic | children autoinflammatory syndrome canakinumab clinical case |
| url | https://vsp.spr-journal.ru/jour/article/view/1677 |
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