EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME

EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME

The article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action...

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Bibliographic Details
Main Authors: Tatyana V. Sleptsova, Еkaterina I. Alexeeva, Тatyana М. Bzarova, Kirill V. Savostyanov, Аlexander A. Pushkov, Kseniya B. Isaeva, Rina V. Denisova, Оlga L. Lomakina
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2016-11-01
Series:Вопросы современной педиатрии
Subjects:
children
autoinflammatory syndrome
canakinumab
clinical case
Online Access:https://vsp.spr-journal.ru/jour/article/view/1677
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Summary:The article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action mechanisms. After 8 weeks of canakinumab therapy, systemic manifestations were cropped, and laboratory parameters of the disease activity were normalized. During the entire care period (12 months), neither serious adverse events nor increased incidence of acute respiratory infections have been reported.
ISSN:1682-5527
1682-5535

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