A Cross-Species Brain Magnetic Resonance Imaging and Histology Database of Vertebrates

Abstract Understanding brain evolution requires detailed comparative analyses of brain structures across species. However, high-resolution anatomical and connective data remain limited for most vertebrates beyond a few well-studied model organisms. To address this gap, we collected postmortem brain...

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Bibliographic Details
Main Authors: Tomokazu Tsurugizawa, Yuji Komaki, Illia Aota, Makoto Suematsu, Chiaki Ohtaka-Maruyama, Takuma Kumamoto
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-05540-5
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Summary:Abstract Understanding brain evolution requires detailed comparative analyses of brain structures across species. However, high-resolution anatomical and connective data remain limited for most vertebrates beyond a few well-studied model organisms. To address this gap, we collected postmortem brain samples from a range of vertebrates, primarily small amniotes, and performed magnetic resonance imaging and histological staining. Here, we present the “Animal Brain Collection (ABC),” a freely accessible database that enables researchers to examine and compare cellular and tissue-level brain architectures across species. This resource provides a foundation for cross-species investigations of brain structure and development, offering new opportunities for research into the diversity and evolution of vertebrate brains.
ISSN:2052-4463