Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover study

This study analyzed the acute and time-course changes following one resistance training (RT) set (1SET) and three sets (3SET) on hemodynamic and physical performance parameters in individuals with different cognitive impairment levels. Thirty-nine individuals (22 women and 17 men aged 80 ± 9 years)...

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Main Authors: Nuno Fonseca, Dulce Esteves, Diogo Luís Marques, Luís Brandão Faíl, Tiago Sousa, Mafalda Pamplona Pinto, Henrique Pereira Neiva, Mikel Izquierdo, Mário Cardoso Marques
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Experimental Gerontology
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Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525000166
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author Nuno Fonseca
Dulce Esteves
Diogo Luís Marques
Luís Brandão Faíl
Tiago Sousa
Mafalda Pamplona Pinto
Henrique Pereira Neiva
Mikel Izquierdo
Mário Cardoso Marques
author_facet Nuno Fonseca
Dulce Esteves
Diogo Luís Marques
Luís Brandão Faíl
Tiago Sousa
Mafalda Pamplona Pinto
Henrique Pereira Neiva
Mikel Izquierdo
Mário Cardoso Marques
author_sort Nuno Fonseca
collection DOAJ
description This study analyzed the acute and time-course changes following one resistance training (RT) set (1SET) and three sets (3SET) on hemodynamic and physical performance parameters in individuals with different cognitive impairment levels. Thirty-nine individuals (22 women and 17 men aged 80 ± 9 years) grouped by cognitive impairment (mild [MILD], moderate [MOD], and severe [SEV]) randomly performed two protocols, each separated by one week, of 1SET or 3SET of 10 repetitions. Before (PRE), immediately (POST), and 72 h after (POST72) protocols, the participants performed the following measurements: systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), 1-kg medicine ball throw (MBT) distance, five-repetition sit-to-stand (STS) time, and handgrip strength (HGS). A three-way ANOVA with repeated measures revealed no significant differences between 1SET and 3SET on SBP, DBP, HR, STS, MBT, and HGS in any group at any time (all p ≥ 0.05). SEV increased SBP and HR from PRE to POST and decreased STS time after 3SET. From POST to POST72, all groups decreased SBP after both protocols, and SEV improved STS time after 3SET and HGS following both protocols. Furthermore, from PRE to POST72, MILD decreased SBP, while SEV improved HGS following 1SET and STS time following 3SET. These findings demonstrate that single and multiple sets cause acute hemodynamic changes, with a tendency to reduce SBP within 72 h. Additionally, individuals with worse cognitive function showed greater adaptive responses over time in physical performance, with 1SET improving HGS and 3SET enhancing STS performance.Trial registration: ClinicalTrials.gov ID: NCT06185010
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spelling doaj-art-765f032357bb496f949fc2fa268ffe992025-08-20T02:14:46ZengElsevierExperimental Gerontology1873-68152025-03-0120111268810.1016/j.exger.2025.112688Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover studyNuno Fonseca0Dulce Esteves1Diogo Luís Marques2Luís Brandão Faíl3Tiago Sousa4Mafalda Pamplona Pinto5Henrique Pereira Neiva6Mikel Izquierdo7Mário Cardoso Marques8Department of Sport Sciences, University of Beira Interior (UBI), Covilhã, PortugalDepartment of Sport Sciences, University of Beira Interior (UBI), Covilhã, Portugal; Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), Covilhã, PortugalDepartment of Sport Sciences, University of Beira Interior (UBI), Covilhã, Portugal; Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), Covilhã, PortugalDepartment of Sport Sciences, University of Beira Interior (UBI), Covilhã, PortugalDepartment of Sport Sciences, University of Beira Interior (UBI), Covilhã, PortugalDepartment of Sport Sciences, University of Beira Interior (UBI), Covilhã, PortugalDepartment of Sport Sciences, University of Beira Interior (UBI), Covilhã, Portugal; Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), Covilhã, PortugalDepartment of Health Sciences, Public University of Navarra (UPNA), Pamplona, SpainDepartment of Sport Sciences, University of Beira Interior (UBI), Covilhã, Portugal; Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), Covilhã, Portugal; Corresponding author at: Department of Sport Sciences, University of Beira Interior, 6201-001 Covilhã, Portugal.This study analyzed the acute and time-course changes following one resistance training (RT) set (1SET) and three sets (3SET) on hemodynamic and physical performance parameters in individuals with different cognitive impairment levels. Thirty-nine individuals (22 women and 17 men aged 80 ± 9 years) grouped by cognitive impairment (mild [MILD], moderate [MOD], and severe [SEV]) randomly performed two protocols, each separated by one week, of 1SET or 3SET of 10 repetitions. Before (PRE), immediately (POST), and 72 h after (POST72) protocols, the participants performed the following measurements: systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), 1-kg medicine ball throw (MBT) distance, five-repetition sit-to-stand (STS) time, and handgrip strength (HGS). A three-way ANOVA with repeated measures revealed no significant differences between 1SET and 3SET on SBP, DBP, HR, STS, MBT, and HGS in any group at any time (all p ≥ 0.05). SEV increased SBP and HR from PRE to POST and decreased STS time after 3SET. From POST to POST72, all groups decreased SBP after both protocols, and SEV improved STS time after 3SET and HGS following both protocols. Furthermore, from PRE to POST72, MILD decreased SBP, while SEV improved HGS following 1SET and STS time following 3SET. These findings demonstrate that single and multiple sets cause acute hemodynamic changes, with a tendency to reduce SBP within 72 h. Additionally, individuals with worse cognitive function showed greater adaptive responses over time in physical performance, with 1SET improving HGS and 3SET enhancing STS performance.Trial registration: ClinicalTrials.gov ID: NCT06185010http://www.sciencedirect.com/science/article/pii/S0531556525000166Cognitive dysfunctionStrength trainingBlood pressureFunctional capacityInstitutionalized persons
spellingShingle Nuno Fonseca
Dulce Esteves
Diogo Luís Marques
Luís Brandão Faíl
Tiago Sousa
Mafalda Pamplona Pinto
Henrique Pereira Neiva
Mikel Izquierdo
Mário Cardoso Marques
Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover study
Experimental Gerontology
Cognitive dysfunction
Strength training
Blood pressure
Functional capacity
Institutionalized persons
title Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover study
title_full Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover study
title_fullStr Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover study
title_full_unstemmed Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover study
title_short Acute and time-course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals: A randomized crossover study
title_sort acute and time course changes in hemodynamic and physical performance parameters following single and multiple resistance training sets in cognitively impaired individuals a randomized crossover study
topic Cognitive dysfunction
Strength training
Blood pressure
Functional capacity
Institutionalized persons
url http://www.sciencedirect.com/science/article/pii/S0531556525000166
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