The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2)

The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2)

Background: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry. Moreover, there is limited cross-protection between the two different serot...

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Bibliographic Details
Main Authors: Yan Wang, Yiyang Fan, Ruixiang Bi, Yapeng Zhao, Wanning Gao, Derong Zhang, Jialin Bai
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Vaccines
Subjects:
rabbit hemorrhagic disease virus
VP60 protein
chimeric RHDV virus-like particle
vaccine
recombinant baculovirus expression system
Online Access:https://www.mdpi.com/2076-393X/13/7/695
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