Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021

BackgroundThis study aims to investigate the impact of high-sodium diet (HSD) on the global burden of aortic aneurysm (AA), analyze its epidemiological trends across different regions, sexes, and age groups, and project future trends.MethodsData were obtained from the Global Burden of Disease Study...

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Main Authors: Xiedong Shen, Weiling Tian, Chun Xue, Xiangfuo Ji, Anqi Qu, Jun Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1653773/full
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author Xiedong Shen
Weiling Tian
Chun Xue
Xiangfuo Ji
Anqi Qu
Jun Lv
author_facet Xiedong Shen
Weiling Tian
Chun Xue
Xiangfuo Ji
Anqi Qu
Jun Lv
author_sort Xiedong Shen
collection DOAJ
description BackgroundThis study aims to investigate the impact of high-sodium diet (HSD) on the global burden of aortic aneurysm (AA), analyze its epidemiological trends across different regions, sexes, and age groups, and project future trends.MethodsData were obtained from the Global Burden of Disease Study 2021 (GBD 2021) to assess the disability-adjusted life years (DALYs) and death cases of AA attributable to HSD (AA-HSD) from 1990 to 2021. A decomposition analysis was conducted to quantify the contributions of population growth, aging, and epidemiological changes to the disease burden. The Nordpred model was used to project trends from 2022 to 2045.ResultsFrom 1990 to 2021, the global DALYs cases of AA-HSD increased by 103%, and death cases increased by 120%. The largest increase in DALYs was observed in low-middle Socio-demographic Index (SDI) regions (234%), with South Asia experiencing the most significant rise (361%). Aging and population growth were the main drivers of the increased DALYs and death cases. While high SDI regions bore a heavier disease burden, relative inequality slightly improved. Projections indicate that from 2022 to 2045, both DALYs and death cases will continue to rise, with males experiencing a higher burden than females.ConclusionHSD significantly contribute to the global burden of AA, particularly in low-middle SDI regions. Moving forward, differentiated strategies should be adopted based on regional development levels, such as reinforcing salt-reduction policies, promoting early screening programs.
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spelling doaj-art-765dfd02e5be4cd69e87d074af4fa6cc2025-08-21T04:10:27ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-08-011210.3389/fnut.2025.16537731653773Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021Xiedong Shen0Weiling Tian1Chun Xue2Xiangfuo Ji3Anqi Qu4Jun Lv5Department of Vascular and Endovascular Surgery, The Second Affiliated Hospital of Naval University, Shanghai, ChinaInterventional Radiology Department, The Second Affiliated Hospital of Naval University, Shanghai, ChinaDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Naval University, Shanghai, ChinaDepartment of Vascular and Endovascular Surgery, The Second Affiliated Hospital of Naval University, Shanghai, ChinaSchool of Public Health, Southern Medical University, Foshan, Guangdong, ChinaDepartment of Emergency, The Second Affiliated Hospital of Naval University, Shanghai, ChinaBackgroundThis study aims to investigate the impact of high-sodium diet (HSD) on the global burden of aortic aneurysm (AA), analyze its epidemiological trends across different regions, sexes, and age groups, and project future trends.MethodsData were obtained from the Global Burden of Disease Study 2021 (GBD 2021) to assess the disability-adjusted life years (DALYs) and death cases of AA attributable to HSD (AA-HSD) from 1990 to 2021. A decomposition analysis was conducted to quantify the contributions of population growth, aging, and epidemiological changes to the disease burden. The Nordpred model was used to project trends from 2022 to 2045.ResultsFrom 1990 to 2021, the global DALYs cases of AA-HSD increased by 103%, and death cases increased by 120%. The largest increase in DALYs was observed in low-middle Socio-demographic Index (SDI) regions (234%), with South Asia experiencing the most significant rise (361%). Aging and population growth were the main drivers of the increased DALYs and death cases. While high SDI regions bore a heavier disease burden, relative inequality slightly improved. Projections indicate that from 2022 to 2045, both DALYs and death cases will continue to rise, with males experiencing a higher burden than females.ConclusionHSD significantly contribute to the global burden of AA, particularly in low-middle SDI regions. Moving forward, differentiated strategies should be adopted based on regional development levels, such as reinforcing salt-reduction policies, promoting early screening programs.https://www.frontiersin.org/articles/10.3389/fnut.2025.1653773/fullaortic aneurysmdiets high in sodiumglobal burden of diseaseSDIDALYs
spellingShingle Xiedong Shen
Weiling Tian
Chun Xue
Xiangfuo Ji
Anqi Qu
Jun Lv
Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021
Frontiers in Nutrition
aortic aneurysm
diets high in sodium
global burden of disease
SDI
DALYs
title Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021
title_full Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021
title_fullStr Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021
title_full_unstemmed Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021
title_short Global burden of aortic aneurysm attributable to high-sodium diet from 1990 to 2021
title_sort global burden of aortic aneurysm attributable to high sodium diet from 1990 to 2021
topic aortic aneurysm
diets high in sodium
global burden of disease
SDI
DALYs
url https://www.frontiersin.org/articles/10.3389/fnut.2025.1653773/full
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