Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach

Hypercholesterolemia can be a consequence of excessive dietary saturated fatty acid (SFA), while almond-supplemented diets can improve lipid profiles. However, the differential and independent impacts of dietary SFA and almondsupplemented diets on plasma total cholesterol (pTC) and low-density lipop...

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Main Authors: Rudy M. Ortiz, Steven Garcia, Arnold D. Kim
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Nutrition and Metabolism
Online Access:http://dx.doi.org/10.1155/2012/265712
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author Rudy M. Ortiz
Steven Garcia
Arnold D. Kim
author_facet Rudy M. Ortiz
Steven Garcia
Arnold D. Kim
author_sort Rudy M. Ortiz
collection DOAJ
description Hypercholesterolemia can be a consequence of excessive dietary saturated fatty acid (SFA), while almond-supplemented diets can improve lipid profiles. However, the differential and independent impacts of dietary SFA and almondsupplemented diets on plasma total cholesterol (pTC) and low-density lipoprotein (pLDL-c) concentrations have not been directly compared and are not well described. We reviewed the available data to construct multiple regression analyses to theoretically assess the impact of relative almond intake (RAI) and dietary SFA on reducing pTC and pLDL-c concentrations. Strong, negative correlations between RAI and percent change in mean pTC (R=0.776;P=0.005) and RAI and percent change in mean pLDL-c (R=0.818;P=0.002) were detected. The relationships between percent change in mean dietary SFA, and percent change in mean pTC and mean pLDL-c were weaker and only significant for pLDL-c. The multiple regression analyses demonstrated modest improvements in the strength of the correlations for both pTC (R=0.804;P=0.016) and pLDL-c (R=0.855;P=0.005). The models suggest that the increase in RAI contributes to the reduction in pTC and pLDL-c to a greater extent than a reduction in dietary SFA, but a simultaneous decrease in dietary SFA should further improve lipid profiles.
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spelling doaj-art-765d104bc71b4a1b85c134b4e578ef242025-08-20T03:35:16ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322012-01-01201210.1155/2012/265712265712Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical ApproachRudy M. Ortiz0Steven Garcia1Arnold D. Kim2Department of Molecular and Cellular Biology, School of Natural Sciences, University of California, Merced, Merced, CA 95343, USADepartment of Molecular and Cellular Biology, School of Natural Sciences, University of California, Merced, Merced, CA 95343, USADepartment of Applied Mathematics, University of California, Merced, Merced, CA 95343, USAHypercholesterolemia can be a consequence of excessive dietary saturated fatty acid (SFA), while almond-supplemented diets can improve lipid profiles. However, the differential and independent impacts of dietary SFA and almondsupplemented diets on plasma total cholesterol (pTC) and low-density lipoprotein (pLDL-c) concentrations have not been directly compared and are not well described. We reviewed the available data to construct multiple regression analyses to theoretically assess the impact of relative almond intake (RAI) and dietary SFA on reducing pTC and pLDL-c concentrations. Strong, negative correlations between RAI and percent change in mean pTC (R=0.776;P=0.005) and RAI and percent change in mean pLDL-c (R=0.818;P=0.002) were detected. The relationships between percent change in mean dietary SFA, and percent change in mean pTC and mean pLDL-c were weaker and only significant for pLDL-c. The multiple regression analyses demonstrated modest improvements in the strength of the correlations for both pTC (R=0.804;P=0.016) and pLDL-c (R=0.855;P=0.005). The models suggest that the increase in RAI contributes to the reduction in pTC and pLDL-c to a greater extent than a reduction in dietary SFA, but a simultaneous decrease in dietary SFA should further improve lipid profiles.http://dx.doi.org/10.1155/2012/265712
spellingShingle Rudy M. Ortiz
Steven Garcia
Arnold D. Kim
Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach
Journal of Nutrition and Metabolism
title Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach
title_full Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach
title_fullStr Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach
title_full_unstemmed Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach
title_short Is Almond Consumption More Effective Than Reduced Dietary Saturated Fat at Decreasing Plasma Total Cholesterol and LDL-c Levels? A Theoretical Approach
title_sort is almond consumption more effective than reduced dietary saturated fat at decreasing plasma total cholesterol and ldl c levels a theoretical approach
url http://dx.doi.org/10.1155/2012/265712
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