Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case report
Abstract Background Thrombus in transit (TIT), a rare and life-threatening condition, poses risks of pulmonary and paradoxical embolism which needs prompt diagnosis. Our case report highlights the significance of utilizing advanced imaging techniques for accurate and timely diagnosis of TIT and the...
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BMC
2025-05-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-025-04798-2 |
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| author | Maryam Mehrpooya Maryam Faramarzpour Mehrzad Rahmanian Parisa Fallahtafti Mohammad Reza Eftekhari |
| author_facet | Maryam Mehrpooya Maryam Faramarzpour Mehrzad Rahmanian Parisa Fallahtafti Mohammad Reza Eftekhari |
| author_sort | Maryam Mehrpooya |
| collection | DOAJ |
| description | Abstract Background Thrombus in transit (TIT), a rare and life-threatening condition, poses risks of pulmonary and paradoxical embolism which needs prompt diagnosis. Our case report highlights the significance of utilizing advanced imaging techniques for accurate and timely diagnosis of TIT and the potential life-saving role of surgical thrombectomy. Case summary This case report discusses a rare instance of biatrial thrombus associated with venous thromboembolism (VTE) and patent foramen ovale (PFO). A 66-year-old female with multiple comorbidities presented with dyspnea and fatigue. Imaging revealed large thrombi in both atria, extending via PFO. Concurrent acute deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) were identified. Emergency cardiac surgery successfully removed the thrombi, emphasizing the diagnostic and management challenges associated with biatrial thrombus and PFO. Conclusion Point-of-care ultrasound (POCUS) plays a critical role in rapidly identifying TIT across a PFO. The time-sensitive and multidisciplinary medical management of TIT is crucial, requiring individualized strategies. Clinical trial number Not applicable. Key clinical message POCUS can be very helpful in providing a more appropriate image and more accurate diagnosis in patients with pulmonary embolism related to thrombus in transit (TIT) which is one of the most life-threatening medical conditions. |
| format | Article |
| id | doaj-art-7657a8b04ae548ba9963c0e8e88cc0c8 |
| institution | OA Journals |
| issn | 1471-2261 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-7657a8b04ae548ba9963c0e8e88cc0c82025-08-20T02:34:06ZengBMCBMC Cardiovascular Disorders1471-22612025-05-012511710.1186/s12872-025-04798-2Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case reportMaryam Mehrpooya0Maryam Faramarzpour1Mehrzad Rahmanian2Parisa Fallahtafti3Mohammad Reza Eftekhari4Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical SciencesDepartment of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical SciencesDepartment of Cardiac Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical SciencesSchool of Medicine, Tehran University of Medical SciencesDepartment of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical SciencesAbstract Background Thrombus in transit (TIT), a rare and life-threatening condition, poses risks of pulmonary and paradoxical embolism which needs prompt diagnosis. Our case report highlights the significance of utilizing advanced imaging techniques for accurate and timely diagnosis of TIT and the potential life-saving role of surgical thrombectomy. Case summary This case report discusses a rare instance of biatrial thrombus associated with venous thromboembolism (VTE) and patent foramen ovale (PFO). A 66-year-old female with multiple comorbidities presented with dyspnea and fatigue. Imaging revealed large thrombi in both atria, extending via PFO. Concurrent acute deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) were identified. Emergency cardiac surgery successfully removed the thrombi, emphasizing the diagnostic and management challenges associated with biatrial thrombus and PFO. Conclusion Point-of-care ultrasound (POCUS) plays a critical role in rapidly identifying TIT across a PFO. The time-sensitive and multidisciplinary medical management of TIT is crucial, requiring individualized strategies. Clinical trial number Not applicable. Key clinical message POCUS can be very helpful in providing a more appropriate image and more accurate diagnosis in patients with pulmonary embolism related to thrombus in transit (TIT) which is one of the most life-threatening medical conditions.https://doi.org/10.1186/s12872-025-04798-2Foramen ovalePatentEchocardiographyThrombectomyThrombosisCase report |
| spellingShingle | Maryam Mehrpooya Maryam Faramarzpour Mehrzad Rahmanian Parisa Fallahtafti Mohammad Reza Eftekhari Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case report BMC Cardiovascular Disorders Foramen ovale Patent Echocardiography Thrombectomy Thrombosis Case report |
| title | Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case report |
| title_full | Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case report |
| title_fullStr | Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case report |
| title_full_unstemmed | Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case report |
| title_short | Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management—a case report |
| title_sort | extensive biatrial thrombus in transit across a patent foramen ovale prompt diagnosis and management a case report |
| topic | Foramen ovale Patent Echocardiography Thrombectomy Thrombosis Case report |
| url | https://doi.org/10.1186/s12872-025-04798-2 |
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