The relationship between May-Thurner syndrome and varicocele in men: a narrative review

May-Thurner syndrome (MTS), defined by compression of the left common iliac vein, increases left gonadal-vein pressure and may underlie otherwise varicoceles. This narrative review synthesises 25 relevant publications: case reports, series, observational and interventional studieas. Pooled evidence...

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Main Authors: Vladimir A. Vorobev, A. P. Chemezov, Kirill M. Su-Yanz, Amirkhon Kh. Iakubov
Format: Article
Language:Russian
Published: ZAO "Consilium Medicum" 2025-01-01
Series:Consilium Medicum
Subjects:
Online Access:https://consilium.orscience.ru/2075-1753/article/viewFile/678910/203988
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author Vladimir A. Vorobev
A. P. Chemezov
Kirill M. Su-Yanz
Amirkhon Kh. Iakubov
author_facet Vladimir A. Vorobev
A. P. Chemezov
Kirill M. Su-Yanz
Amirkhon Kh. Iakubov
author_sort Vladimir A. Vorobev
collection DOAJ
description May-Thurner syndrome (MTS), defined by compression of the left common iliac vein, increases left gonadal-vein pressure and may underlie otherwise varicoceles. This narrative review synthesises 25 relevant publications: case reports, series, observational and interventional studieas. Pooled evidence indicates that 67–90% of men with varicocele exhibit at least 25% iliac-venous compression, and that successful iliac stenting leads to regression of varicocele symptoms and improved fertility. The diagnostic value of combining duplex ultrasound with computed tomographic/magnetic resonance venography is highlighted, whereas catheter venography with intravascular ultrasound remains the reference for confirming haemodynamic significance. Gaps in data regarding long-term stent patency and the epidemiology of MTS in asymptomatic males have been identified. It advocates systematic iliac-vein assessment in men presenting with recurrent or bilateral varicocele and calls for prospective multicentre trials comparing surgical ligation with endovascular correction.
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issn 2075-1753
2542-2170
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spelling doaj-art-764fac08292a441ca102be5f38bef7b42025-08-20T03:59:36ZrusZAO "Consilium Medicum"Consilium Medicum2075-17532542-21702025-01-0127738038410.26442/20751753.2025.7.2032824963The relationship between May-Thurner syndrome and varicocele in men: a narrative reviewVladimir A. Vorobev0https://orcid.org/0000-0003-3285-5559A. P. Chemezov1https://orcid.org/0009-0009-0939-8186Kirill M. Su-Yanz2https://orcid.org/0009-0005-9143-916XAmirkhon Kh. Iakubov3https://orcid.org/0009-0006-2892-0900Irkutsk State Medical UniversityIrkutsk State Medical UniversityIrkutsk State Medical UniversityIrkutsk State Medical UniversityMay-Thurner syndrome (MTS), defined by compression of the left common iliac vein, increases left gonadal-vein pressure and may underlie otherwise varicoceles. This narrative review synthesises 25 relevant publications: case reports, series, observational and interventional studieas. Pooled evidence indicates that 67–90% of men with varicocele exhibit at least 25% iliac-venous compression, and that successful iliac stenting leads to regression of varicocele symptoms and improved fertility. The diagnostic value of combining duplex ultrasound with computed tomographic/magnetic resonance venography is highlighted, whereas catheter venography with intravascular ultrasound remains the reference for confirming haemodynamic significance. Gaps in data regarding long-term stent patency and the epidemiology of MTS in asymptomatic males have been identified. It advocates systematic iliac-vein assessment in men presenting with recurrent or bilateral varicocele and calls for prospective multicentre trials comparing surgical ligation with endovascular correction.https://consilium.orscience.ru/2075-1753/article/viewFile/678910/203988may-thurner syndromevaricocelevenous compressionmale infertilityendovascular treatment
spellingShingle Vladimir A. Vorobev
A. P. Chemezov
Kirill M. Su-Yanz
Amirkhon Kh. Iakubov
The relationship between May-Thurner syndrome and varicocele in men: a narrative review
Consilium Medicum
may-thurner syndrome
varicocele
venous compression
male infertility
endovascular treatment
title The relationship between May-Thurner syndrome and varicocele in men: a narrative review
title_full The relationship between May-Thurner syndrome and varicocele in men: a narrative review
title_fullStr The relationship between May-Thurner syndrome and varicocele in men: a narrative review
title_full_unstemmed The relationship between May-Thurner syndrome and varicocele in men: a narrative review
title_short The relationship between May-Thurner syndrome and varicocele in men: a narrative review
title_sort relationship between may thurner syndrome and varicocele in men a narrative review
topic may-thurner syndrome
varicocele
venous compression
male infertility
endovascular treatment
url https://consilium.orscience.ru/2075-1753/article/viewFile/678910/203988
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