Comparative evaluation of DNA and RNA probes for capture-based mitochondrial DNA next-generation sequencing
Abstract Background Probe-based liquid-phase hybridization capture is a powerful and commonly used approach for next-generation sequencing (NGS) of mitochondrial DNA (mtDNA). However, the performance difference between DNA and RNA probe-based capture strategies for mtDNA NGS remains to be determined...
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| Main Authors: | Tianlei Sun, Shengjing Li, Yang Liu, Kaixiang Zhou, Jiamin Wang, Zhangwen Lei, Xu Guo, Jinliang Xing, Wenjie Guo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | BMC Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12915-025-02365-x |
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