Lutein Protects Ischemic Skin Flaps via Antioxidant and Anti-Inflammatory Mechanisms in a Rat Model of Ischemia-Reperfusion Injury

Background Ischemia-reperfusion injury is a well-recognized challenge in reconstructive flap surgery, often leading to partial or total tissue necrosis. In this experimental study, we aimed to evaluate the protective effects of lutein—a non-provitamin A carotenoid known for its antioxidant and anti-...

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Bibliographic Details
Main Authors: Ovunc Akdemir, Atilla Eyuboglu, Emel Oyku Cetin, Yigit Uyanikgil
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Investigative Surgery
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Online Access:https://www.tandfonline.com/doi/10.1080/08941939.2025.2528341
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