The lipid-lowering therapy effectiveness and IHD course after coronary stenting
Objective: to examine the relationship between the achievement of goal lipid metabolism and incidence of adverse cardiovascular events in patients after successful coronary stenting. Materials and Methods: The database for the study was data from 198 histories of patients with various forms of ische...
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Dnipro State Medical University
2013-06-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://medpers.dsma.dp.ua/issues/2013/N2/46-54.pdf |
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| author | Skoromna A.S. Khomych A.V. Romanenko S.V. Koval O.A. |
| author_facet | Skoromna A.S. Khomych A.V. Romanenko S.V. Koval O.A. |
| author_sort | Skoromna A.S. |
| collection | DOAJ |
| description | Objective: to examine the relationship between the achievement of goal lipid metabolism and incidence of adverse cardiovascular events in patients after successful coronary stenting. Materials and Methods: The database for the study was data from 198 histories of patients with various forms of ischemic heart disease, who underwent coronary angiography, 306 stents implanted in coronary arteries in a regional cardiology center and Mechnikov regional hospital, Dnepropetrovsk over the period from 2004 to 2008. The period of observation of patients was on average 4,6 ± 1,3 years. Results and Discussion: The study found that the best five-year survival rate of patients without adverse cardiovascular events after stenting was significantly associated with previous PCI, presence of stable angina not higher than 2nd FC (61%, p<0,0001), achieving target level of CH-LDL (35%, p = 0.014), TG level less than 1,7 mmol/l was associated with a sta¬tistically significant reduction in risk of the primary endpoint 0,68 (long-rank p <0,0001) while taking statins after stenting. Conclusions: Achieving level of total cholesterol less than 4.5 mmol / L was not significantly associated with a decrease in the frequency of adverse CAP after successful stenting, but the level of 5-year survival was significantly associated with the achievement of target levels of LDL cholesterol, less than 2.5 mg/dL and triglycerides less than 1.7 mmol/l. |
| format | Article |
| id | doaj-art-763229f18b244bc38dc0eddb1b84c886 |
| institution | DOAJ |
| issn | 2307-0404 2307-0404 |
| language | English |
| publishDate | 2013-06-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-763229f18b244bc38dc0eddb1b84c8862025-08-20T02:50:47ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042307-04042013-06-011824654The lipid-lowering therapy effectiveness and IHD course after coronary stentingSkoromna A.S.0Khomych A.V.1Romanenko S.V.2Koval O.A. 3SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»SE “Dnipropetrovsk regional clinical centre of cardiology and cardiac surgery”SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»Objective: to examine the relationship between the achievement of goal lipid metabolism and incidence of adverse cardiovascular events in patients after successful coronary stenting. Materials and Methods: The database for the study was data from 198 histories of patients with various forms of ischemic heart disease, who underwent coronary angiography, 306 stents implanted in coronary arteries in a regional cardiology center and Mechnikov regional hospital, Dnepropetrovsk over the period from 2004 to 2008. The period of observation of patients was on average 4,6 ± 1,3 years. Results and Discussion: The study found that the best five-year survival rate of patients without adverse cardiovascular events after stenting was significantly associated with previous PCI, presence of stable angina not higher than 2nd FC (61%, p<0,0001), achieving target level of CH-LDL (35%, p = 0.014), TG level less than 1,7 mmol/l was associated with a sta¬tistically significant reduction in risk of the primary endpoint 0,68 (long-rank p <0,0001) while taking statins after stenting. Conclusions: Achieving level of total cholesterol less than 4.5 mmol / L was not significantly associated with a decrease in the frequency of adverse CAP after successful stenting, but the level of 5-year survival was significantly associated with the achievement of target levels of LDL cholesterol, less than 2.5 mg/dL and triglycerides less than 1.7 mmol/l.http://medpers.dsma.dp.ua/issues/2013/N2/46-54.pdfchronic ischemic heart diseasecoronary stentinglipid profilestatins |
| spellingShingle | Skoromna A.S. Khomych A.V. Romanenko S.V. Koval O.A. The lipid-lowering therapy effectiveness and IHD course after coronary stenting Medičnì Perspektivi chronic ischemic heart disease coronary stenting lipid profile statins |
| title | The lipid-lowering therapy effectiveness and IHD course after coronary stenting |
| title_full | The lipid-lowering therapy effectiveness and IHD course after coronary stenting |
| title_fullStr | The lipid-lowering therapy effectiveness and IHD course after coronary stenting |
| title_full_unstemmed | The lipid-lowering therapy effectiveness and IHD course after coronary stenting |
| title_short | The lipid-lowering therapy effectiveness and IHD course after coronary stenting |
| title_sort | lipid lowering therapy effectiveness and ihd course after coronary stenting |
| topic | chronic ischemic heart disease coronary stenting lipid profile statins |
| url | http://medpers.dsma.dp.ua/issues/2013/N2/46-54.pdf |
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