Analysis of the link between the redox state and enzymatic activity of the HtrA (DegP) protein from Escherichia coli.

Analysis of the link between the redox state and enzymatic activity of the HtrA (DegP) protein from Escherichia coli.

Bacterial HtrAs are proteases engaged in extracytoplasmic activities during stressful conditions and pathogenesis. A model prokaryotic HtrA (HtrA/DegP from Escherichia coli) requires activation to cleave its substrates efficiently. In the inactive state of the enzyme, one of the regulatory loops, te...

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Main Authors: Tomasz Koper, Agnieszka Polit, Anna Sobiecka-Szkatula, Katarzyna Wegrzyn, Andrea Scire, Donata Figaj, Leszek Kadzinski, Urszula Zarzecka, Dorota Zurawa-Janicka, Bogdan Banecki, Adam Lesner, Fabio Tanfani, Barbara Lipinska, Joanna Skorko-Glonek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117413&type=printable
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