Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial Infarction
Background. Khat chewing is a common habit in Yemen despite increased evidence of its negative impact on the cardiovascular system. Aims. We aimed to study the epicardial coronary arteries in khat chewers presenting with myocardial infarction (AMI). Materials and Methods. A descriptive, cross-sectio...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/857019 |
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| author | Ahmed Al-Motarreb Adel Shabana Ayman El-Menyar |
| author_facet | Ahmed Al-Motarreb Adel Shabana Ayman El-Menyar |
| author_sort | Ahmed Al-Motarreb |
| collection | DOAJ |
| description | Background. Khat chewing is a common habit in Yemen despite increased evidence of its negative impact on the cardiovascular system. Aims. We aimed to study the epicardial coronary arteries in khat chewers presenting with myocardial infarction (AMI). Materials and Methods. A descriptive, cross-sectional study was conducted between November 2008 and May 2009 in Yemen. AMI patients who underwent coronary angiogram were enrolled and divided into groups (gp): gp1 (diabetic and khat chewers), gp2 (khat chewers and nondiabetic), and gp3 (diabetic and non-khat users). Results. Of 347 AMI patients 63%, 21%, and 16% were in gp 2, 3, and 1, respectively. Khat chewers were younger in comparison to non-khat users. Group 3 patients were more likely to have multivessel disease, severe left anterior descending (LAD), right coronary artery (RCA) stenosis and total RCA, and left circumflex (Lcx) occlusion compared to other groups. Group 1 patients were more likely to have total LAD occlusion and severe Lcx lesions. In multivariate analysis, age, diabetes mellitus, and smoking were significant independent predictors for significant coronary artery lesions; however, khat chewing did not show such association. Conclusions. Coronary spasm is the main mechanism of AMI in khat chewers. The impact of our finding for risk stratification and management warrants further studies. |
| format | Article |
| id | doaj-art-762bffed653b4becacebed397ac0e63b |
| institution | Kabale University |
| issn | 2090-2824 2090-2832 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Vascular Medicine |
| spelling | doaj-art-762bffed653b4becacebed397ac0e63b2025-02-03T01:25:24ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322013-01-01201310.1155/2013/857019857019Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial InfarctionAhmed Al-Motarreb0Adel Shabana1Ayman El-Menyar2Department of Cardiology, Faculty of Medicine, Sana’a University, Sana’a 13078, YemenDepartment of Cardiology, Heart Hospital, Hamad Medical Corporation, 3050 Doha, QatarClinical Medicine, Weill Cornell Medical College, 24144 Doha, QatarBackground. Khat chewing is a common habit in Yemen despite increased evidence of its negative impact on the cardiovascular system. Aims. We aimed to study the epicardial coronary arteries in khat chewers presenting with myocardial infarction (AMI). Materials and Methods. A descriptive, cross-sectional study was conducted between November 2008 and May 2009 in Yemen. AMI patients who underwent coronary angiogram were enrolled and divided into groups (gp): gp1 (diabetic and khat chewers), gp2 (khat chewers and nondiabetic), and gp3 (diabetic and non-khat users). Results. Of 347 AMI patients 63%, 21%, and 16% were in gp 2, 3, and 1, respectively. Khat chewers were younger in comparison to non-khat users. Group 3 patients were more likely to have multivessel disease, severe left anterior descending (LAD), right coronary artery (RCA) stenosis and total RCA, and left circumflex (Lcx) occlusion compared to other groups. Group 1 patients were more likely to have total LAD occlusion and severe Lcx lesions. In multivariate analysis, age, diabetes mellitus, and smoking were significant independent predictors for significant coronary artery lesions; however, khat chewing did not show such association. Conclusions. Coronary spasm is the main mechanism of AMI in khat chewers. The impact of our finding for risk stratification and management warrants further studies.http://dx.doi.org/10.1155/2013/857019 |
| spellingShingle | Ahmed Al-Motarreb Adel Shabana Ayman El-Menyar Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial Infarction International Journal of Vascular Medicine |
| title | Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial Infarction |
| title_full | Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial Infarction |
| title_fullStr | Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial Infarction |
| title_full_unstemmed | Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial Infarction |
| title_short | Epicardial Coronary Arteries in Khat Chewers Presenting with Myocardial Infarction |
| title_sort | epicardial coronary arteries in khat chewers presenting with myocardial infarction |
| url | http://dx.doi.org/10.1155/2013/857019 |
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