Prune Belly Syndrome Associated with Interstitial 17q12 Microdeletion

We report a term male neonate presenting with a “prune belly,” bilateral hydronephrosis, hydroureter, posterior urethral obstruction, and bilateral undescended testes. Analysis with the whole genome SNP microarray revealed an interstitial deletion of about 1.49 megabase (MB) at chromosome 17q12. We...

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Main Authors: Surasak Puvabanditsin, Miry Shim, Jeffrey Suell, Jeffrey Manzano, Kristin Blackledge, Avram Bursky-Tammam, Rajeev Mehta
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2022/7364286
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author Surasak Puvabanditsin
Miry Shim
Jeffrey Suell
Jeffrey Manzano
Kristin Blackledge
Avram Bursky-Tammam
Rajeev Mehta
author_facet Surasak Puvabanditsin
Miry Shim
Jeffrey Suell
Jeffrey Manzano
Kristin Blackledge
Avram Bursky-Tammam
Rajeev Mehta
author_sort Surasak Puvabanditsin
collection DOAJ
description We report a term male neonate presenting with a “prune belly,” bilateral hydronephrosis, hydroureter, posterior urethral obstruction, and bilateral undescended testes. Analysis with the whole genome SNP microarray revealed an interstitial deletion of about 1.49 megabase (MB) at chromosome 17q12. We present a rare association of prune belly syndrome with a chromosomal deletion in this same region.
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language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Case Reports in Urology
spelling doaj-art-7622fb52d5fd4b8e9589b551e58ecfbd2025-08-20T02:07:15ZengWileyCase Reports in Urology2090-69782022-01-01202210.1155/2022/7364286Prune Belly Syndrome Associated with Interstitial 17q12 MicrodeletionSurasak Puvabanditsin0Miry Shim1Jeffrey Suell2Jeffrey Manzano3Kristin Blackledge4Avram Bursky-Tammam5Rajeev Mehta6Department of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsWe report a term male neonate presenting with a “prune belly,” bilateral hydronephrosis, hydroureter, posterior urethral obstruction, and bilateral undescended testes. Analysis with the whole genome SNP microarray revealed an interstitial deletion of about 1.49 megabase (MB) at chromosome 17q12. We present a rare association of prune belly syndrome with a chromosomal deletion in this same region.http://dx.doi.org/10.1155/2022/7364286
spellingShingle Surasak Puvabanditsin
Miry Shim
Jeffrey Suell
Jeffrey Manzano
Kristin Blackledge
Avram Bursky-Tammam
Rajeev Mehta
Prune Belly Syndrome Associated with Interstitial 17q12 Microdeletion
Case Reports in Urology
title Prune Belly Syndrome Associated with Interstitial 17q12 Microdeletion
title_full Prune Belly Syndrome Associated with Interstitial 17q12 Microdeletion
title_fullStr Prune Belly Syndrome Associated with Interstitial 17q12 Microdeletion
title_full_unstemmed Prune Belly Syndrome Associated with Interstitial 17q12 Microdeletion
title_short Prune Belly Syndrome Associated with Interstitial 17q12 Microdeletion
title_sort prune belly syndrome associated with interstitial 17q12 microdeletion
url http://dx.doi.org/10.1155/2022/7364286
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